ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for ESOPHAGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New combo therapy aims to keep esophageal cancer from coming back
Disease control CompletedThis study tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiotherapy after surgery could help prevent esophageal cancer from returning in patients at high risk of recurrence. 26 adults with locally advanced esophageal squamous cell carcinoma who had…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated May 17, 2026 01:04 UTC
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New pill for advanced cancers enters first human tests
Disease control CompletedThis early-phase study tested an experimental oral drug called JAB-3312 in 40 adults with advanced solid tumors (such as lung, colon, or breast cancer) that had stopped responding to standard treatments. The main goal was to find a safe dose and understand side effects. Participa…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Jacobio Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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AI predicts cancer disappearance after immunotherapy in esophageal patients
Diagnosis CompletedThis study looked at medical records and CT scans of 363 adults with esophageal cancer who received chemotherapy and immunotherapy before surgery. Researchers built a computer model that combines patient info, CT image features, and deep learning to predict whether the cancer is …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Nanjing Medical University • Aim: Diagnosis
Last updated May 15, 2026 11:54 UTC
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New cancer drug SGN-B6A tested for safety in chinese patients
Symptom relief CompletedThis early-stage study tested a new drug called SGN-B6A in 6 Chinese adults with advanced solid tumors (lung, head/neck, esophageal, or stomach cancers) that had stopped responding to standard treatments. The main goal was to check the drug's safety and side effects, and to see h…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Diabetes may worsen esophageal cancer surgery outcomes, study finds
Knowledge-focused CompletedThis study looked at 605 patients with esophageal cancer who had minimally invasive surgery to remove their esophagus. Researchers wanted to see if having type 2 diabetes affected how well patients recovered and how long they lived. They also checked if diabetes medication (metfo…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Knowledge-focused
Last updated May 17, 2026 01:00 UTC
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Artery-Sparing surgery may reduce complications after esophageal cancer removal
Knowledge-focused CompletedThis study looked at 120 people with esophageal cancer who had a specific type of surgery (McKeown esophagectomy). Researchers compared keeping the right gastric artery intact versus cutting it, to see which approach led to fewer problems like leaks or narrowing at the surgical c…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: The First Hospital of Hebei Medical University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Feeding tube study seeks best recovery route after esophageal cancer surgery
Knowledge-focused CompletedThis study looked at 577 people who had surgery for esophageal cancer. It compared two ways of giving nutrition after surgery: a tube placed directly into the small intestine (jejunostomy) versus a tube through the nose into the stomach (nasoenteric). The goal was to see if one m…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC