ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for ESOPHAGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New drug duo shows promise for tough cancers
Disease control CompletedThis study tested two experimental drugs (AK104 and AK117) together, sometimes with chemotherapy, in 128 people with advanced solid tumors. The goal was to see if the combination is safe and can shrink tumors. It focused on patients with stomach, esophageal, or other advanced can…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New drug cocktail shows promise against tough esophageal cancer
Disease control CompletedThis study tested whether adding an experimental drug called LBL-007 to standard immunotherapy and chemotherapy helps shrink tumors better in people with advanced esophageal cancer that cannot be surgically removed. About 118 participants received either the three-drug combo or t…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: BeiGene • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Immunotherapy duo shows promise in Tough-to-Treat esophageal cancer
Disease control CompletedThis phase 3 trial tested whether adding two immunotherapy drugs, atezolizumab and tiragolumab, to standard chemotherapy could help people with advanced esophageal cancer live longer. About 461 participants received either the immunotherapy combo plus chemo or a placebo plus chem…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Immunotherapy combo shows promise in preventing esophageal cancer return
Disease control CompletedThis study tested whether adding the immunotherapy drug pembrolizumab after standard chemoradiotherapy and surgery could prevent cancer recurrence in 26 patients with high-risk esophageal squamous cell carcinoma. Participants received cisplatin-based chemoradiotherapy followed by…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Immunotherapy duo shows promise against tough esophageal cancer
Disease control CompletedThis phase 3 trial tested whether adding immunotherapy drugs (nivolumab and ipilimumab) to standard chemotherapy helps people with advanced esophageal cancer live longer or keep their cancer from growing. About 970 participants with inoperable or metastatic esophageal squamous ce…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Artery-Saving surgery may reduce complications after esophageal cancer removal
Disease control CompletedThis study looked at 120 people with esophageal cancer who had a type of surgery called McKeown esophagectomy. Half had the right gastric artery preserved, and half had it tied off. The goal was to see if preserving the artery lowers the chance of leaks or narrowing where the new…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: The First Hospital of Hebei Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New pill JAB-3312 tested in patients with advanced cancers
Disease control CompletedThis early-stage trial tested an oral drug called JAB-3312 in 40 adults with advanced solid tumors (like lung, colon, or breast cancer) that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects. Researchers also looked …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Jacobio Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New cancer drug SGN-B6A tested for safety in chinese patients
Disease control CompletedThis early-stage trial tested the safety of a new drug called SGN-B6A in 6 Chinese patients with advanced solid tumors (lung, head and neck, esophageal, stomach cancers). The main goal was to identify side effects and see how the body processes the drug. It is a first step to see…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New AI reads CT scans to predict which esophageal cancers vanish after treatment
Diagnosis CompletedThis study tested whether a computer model could predict if esophageal cancer completely disappears after chemo-immunotherapy. Researchers reviewed medical records and CT scans from 363 patients who received standard treatment before surgery. The AI combined clinical data, radiom…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Nanjing Medical University • Aim: Diagnosis
Last updated Jun 26, 2026 18:28 UTC
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Which chemo works better for esophageal cancer? study compares two common drugs
Knowledge-focused CompletedThis study looked back at 387 patients with esophageal cancer to compare two chemotherapy drugs, nab-paclitaxel and paclitaxel, given before surgery. The goal was to see which drug leads to better outcomes like complete cancer removal. The study is completed, but results are not …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Sichuan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Dye test could catch hidden cancer in achalasia patients
Knowledge-focused CompletedPeople with achalasia, a swallowing disorder, have a much higher risk of developing esophageal cancer. This study tested whether spraying a special dye (Lugol) during an endoscopy could help doctors find early signs of cancer (dysplasia) in 39 patients who had achalasia for over …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Which feeding tube is best after esophageal cancer surgery?
Knowledge-focused CompletedThis study looked at 577 patients who had surgery for esophageal cancer. Researchers compared two ways of giving nutrition after surgery: feeding through a tube placed directly into the small intestine (jejunostomy) versus a tube through the nose into the stomach (nasoenteric). T…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Diabetes may worsen outcomes after esophageal cancer surgery, study finds
Knowledge-focused CompletedThis study looked at 605 patients with esophageal cancer who had minimally invasive surgery to remove their esophagus. Researchers compared those with and without type 2 diabetes to see if diabetes affected short-term complications and long-term survival. The goal is to understan…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC