Double punch against tough cancer: can new drug combo help control advanced esophageal tumors?

NCT ID NCT04540211

Completed Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 trial tested whether adding two new immunotherapy drugs (atezolizumab and tiragolumab) to standard chemotherapy could better control advanced esophageal cancer that cannot be surgically removed. The study involved 461 patients and directly compared the new combination against standard chemotherapy plus a placebo. The main goals were to see if the new treatment helped patients live longer and kept the cancer from growing for a longer time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Affiliated Hopsital of Jining Medical University

Jining, China
Affiliated Hospital of Chengde Medical University

Chengde, 067020, China
Affiliated Hospital of Jiangnan University(Wuxi Fourth People's Hospital )

Wuxi, 214122, China
Anhui Province Cancer Hospital

Hefei, 12345, China
Anhui Provincial Hospital

Anhui, 230001, China
Anyang Tumor Hosptial

Anyang, 455000, China
Asan Medical Center

Seoul, 05505, South Korea
Beijing Cancer Hospital

Beijing, 100142, China
Beijing Luhe Hospital Capital Medical University

Beijing, China
Cancer Hospital of Shantou University Medical College

Shantou, 515041, China
Chang Gung Medical Foundation - Kaohsiung

Kaohisung, Taiwan
Chongqing Sanxia Central Hospital

Chongqing, 404000, China
Chulalongkorn Hospital

Bangkok, 10330, Thailand
First Affiliated Hospital of Medical College of Xi'an Jiaotong University

Xi'an, 710061, China
Fudan University Shanghai Cancer Center

Shanghai, 200120, China
Fujian Cancer Hospital

Fuzhou, 350014, China
Fujian Provincial Hospital

Fuzhou, China
Gansu Province People Hospital

Lanzhou, 730000, China
Henan Cancer Hospital

Zhengzhou, 450008, China
Huai'an First People's Hospital

Huai'an, China
Hubei Cancer Hospital

Wuhan, 430079, China
Hunan Cancer Hospital

Changsha, 410013, China
Jiangsu Cancer Hospital

Nanjing, 211100, China
Jiangsu Province Hospital of Chinese Medicine

Nanjing, 210029, China
Jilin Cancer Hospital

Changchun, 132013, China
Korea University Guro Hospital

Seoul, 08308, South Korea
Kyungpook National University Chilgok Hospital

Daegu, 41404, South Korea
Liaoning Provincial Cancer Hospital

Shengyang, 110042, China
Linyishi Cancer Hospital

Linyi, 276034, China
Nan Tong Tumor Hospital

Nantong, 226361, China
National Cancer Center

Goyang-si, 10408, South Korea
National Cheng Kung University Hospital

Tainan, 00704, Taiwan
National Taiwan University Hospital

Zhongzheng Dist., 10048, Taiwan
Northern Jangsu People's Hospital

Yangzhou, 225001, China
Prince of Wales Hosp

Shatin, Hong Kong
Queen Mary Hospital

Hong Kong, Hong Kong
Rajavithi Hospital

Bangkok, 10400, Thailand
Ramathibodi Hospital

Bangkok, 10400, Thailand
Samsung Medical Center

Seoul, 06351, South Korea
Seoul National University Bundang Hospital

Seongnam-si, 13605, South Korea
Severance Hospital, Yonsei University Health System

Seoul, 03722, South Korea
Shanghai Chest Hospital

Shanghai, 200000, China
Sichuan Provincial Cancer Hospital

Chengdu, 610041, China
Siriraj Hospital

Bangkok, 10700, Thailand
Songklanagarind Hospital

Songkhla, 90110, Thailand
Southern Medical University Nanfang Hospital

Guangdong Province Guangzhou City, 510515, China
Suining Central Hospital

Suining, 629000, China
Taipei Veterans General Hospital

Taipei, 112201, Taiwan
The First Affiliated Hospital of Xiamen University

Xiamen, 361003, China
The First Affiliated Hospital of Xinxiang Medical University

Xinxiang, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, 450052, China
The First People's Hospital of Lian Yun Gang

Lianyungang, 222002, China
The Second Affiliated Hospital of Anhui Medical University

Hefei, 230601, China
The Second Affiliated Hospital of The Fourth Military Medical University (Tangdu Hospital)

Xi'an, 710038, China
The Second People's Hospital of Huai'an

Huai'an, China
Tianjin Cancer Hospital

Tianjin, 300060, China
Weifang People's Hospital

Weifang, China
West China Hospital, Sichuan University

Chengdu, 610041, China
Wuhan Union Hospital Tongji Medical College, Huazhong University of Science and Technology

Wuhan, 430022, China
Xiangyang Central Hospital

Xiangyang, China
Xuzhou Central Hospital

Xuzhou, China
Zhejiang Cancer Hospital

Hangzhou, 310022, China
Zhongshan Hospital Fudan University

Shanghai, 200032, China
Zhongshan Hospital Xiamen University

Xiamen, 361004, China

Conditions

Explore the condition pages connected to this study.

ESOPHAGEAL CANCER