END STAGE RENAL DISEASE (ESRD)

This completed study tested an oral supplement made from generally recognized as safe (GRAS) ingredients in 8 people with end-stage kidney disease. Two participants had not produced urine for 16 and 22 years. The goal was to see if the supplement could restore even a small amount…

This study tested whether taking probiotics or synbiotics (probiotics plus fiber) for 6 months could improve health in 60 adults with kidney failure on dialysis. Researchers measured changes in blood toxins, heart health, quality of life, and thinking ability. The goal was to see…

This study tested whether taking oral L-carnitine (a natural supplement) three times a week for three months could reduce inflammation and improve nutrition in 50 adults with advanced kidney failure on chronic hemodialysis. Participants were randomly assigned to receive either L-…

This study tested whether an electronic stethoscope can help doctors detect narrowing (stenosis) of the arteriovenous fistula in hemodialysis patients. Researchers collected sound recordings from 30 adults on long-term dialysis over 3 months. The goal was to see if the device cou…

This study looked at whether smelling geranium essential oil can help reduce tiredness and improve sleep in people receiving dialysis for kidney failure. 90 adults on dialysis took part in a crossover trial where they received both the aromatherapy and a placebo at different time…

This study tested whether a home-based exercise program can reduce low back pain and improve quality of life in 30 adults receiving peritoneal dialysis for end-stage kidney disease. Participants followed a structured exercise routine while continuing their usual dialysis care. Re…

This study looked at how the drug LY3537031 moves through the body in people with different levels of kidney function. It included 31 adults with normal kidneys, kidney impairment, or end-stage kidney disease. The goal was to measure drug levels in the blood and how long it takes…

This study looked at 395 adults on long-term dialysis to find out how often their blood pressure drops dangerously during treatment and what makes it more likely. Researchers collected information on patients' health history, medications, and dialysis settings. The goal is to hel…

This completed Phase 1 study looked at how the drug avacopan is processed in 13 people with normal kidney function and those with end-stage renal disease requiring hemodialysis. Researchers measured drug levels in the blood and dialysis fluid after a single dose. The goal was to …

This study looked at whether eating at different times during hemodialysis affects blood pressure stability and how well the treatment removes waste from the body. Researchers divided 40 adults with chronic kidney disease into groups that ate at set times or followed their usual …

This study used a special MRI technique to measure phosphate and ATP (energy) levels inside muscle cells of 11 kidney dialysis patients during a 4-hour session. The goal was to find out whether phosphate removed during dialysis comes from inside cells. If it does, it might explai…