Kidney drug study: does dialysis change how avacopan works?

NCT ID NCT06468826

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 27 times

Summary

This study looked at how the body processes a single dose of the drug avacopan in 13 people—some with healthy kidneys and some with end-stage renal disease (ESRD) who need dialysis. Researchers measured drug levels in the blood and how much was removed by dialysis. The goal was to understand if kidney failure changes how the drug works, which helps doctors decide on proper dosing for ESRD patients.

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Contacts and locations

Locations

  • Floridian Clinical Research, LLC

    Miami Lakes, Florida, 33016, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809-3017, United States

Conditions

Explore the condition pages connected to this study.