END STAGE RENAL DISEASE (ESRD)

This study tests whether a smartphone app and WeChat can help people on long-term dialysis manage their diet, exercise, and medications. About 392 adults with end-stage kidney disease will either get app-based support or standard care. Researchers will track deaths, hospital stay…

This study tests a new device that creates dialysis access through a small skin puncture instead of open surgery. It involves 126 adults with kidney failure who need dialysis. The goal is to see if the procedure is safe and works well, with participants followed for up to five ye…

This study tests a new device called the InnAVasc graft, which is placed under the skin to connect an artery and vein for dialysis. It includes 133 adults with end-stage kidney disease who need a graft for hemodialysis. The main goals are to see if the graft stays open and workin…

This study watches how well the EndoForce System works over time for people with end-stage kidney disease who need a graft for dialysis. It is not testing a new treatment—the device is already FDA-approved. Researchers will track safety issues and how long the graft stays open an…

This study looks at whether a plant-focused diet can improve nutrition in adults with end-stage kidney disease who are on peritoneal dialysis and are malnourished. About 100 participants will be randomly assigned to either a plant-focused diet or a standard kidney diet and follow…

This study looks at whether exercising during dialysis or right before it works better for people with kidney failure. About 72 adults on dialysis will be split into two groups and do supervised exercises twice a week for 12 weeks. The goal is to see which timing improves walking…

This study looks at a rare but serious condition called calciphylaxis, where small blood vessels in the skin harden, often in people with advanced kidney disease. Researchers will compare 860 kidney disease patients with and without calciphylaxis to find clues about what causes i…

This study looks at whether changing the magnesium level in the dialysis fluid can reduce blood cell activation and clotting during treatment. 15 adults on hemodialysis will have their blood and the used dialysis circuit tested after sessions with different fluid compositions. Th…