END STAGE RENAL DISEASE (ESRD)

This study tests a new device that creates a connection between an artery and a vein using a small needle puncture instead of open surgery. The goal is to provide a reliable access point for dialysis in people with kidney failure. About 126 adults will be enrolled and followed fo…

This study looks at whether a plant-focused diet can help malnourished adults on peritoneal dialysis (a type of kidney treatment) improve their nutrition and overall health. About 100 participants will be randomly assigned to either a plant-focused diet or a standard kidney diet …

This study tracks 150 adults with end-stage kidney disease who use the EndoForce System to connect a dialysis graft to a vein. The device is already FDA-approved, so this is not an experiment—it's a check on long-term safety and how well it works over time. Researchers will monit…

This study tests a new device called the InnAVasc graft, which is surgically placed in the arm to provide a reliable access point for hemodialysis in people with end-stage kidney disease. About 133 participants will receive the graft and be followed for two years to see how well …

This trial tests whether a smartphone app (Yueya mini-program and WeChat) can help people with end-stage renal disease who are on maintenance hemodialysis. The app provides personalized guidance on diet, exercise, medications, and health monitoring. Researchers will compare outco…

This study tests whether doing physical therapy during dialysis or just before it works better for people with end-stage kidney disease. 72 adults on hemodialysis will be split into two groups and exercise twice a week for 12 weeks. Researchers will measure walking ability, stren…

This study looks at whether making changes at hospitals and dialysis centers can help more people with kidney failure start the process to get a transplant. About 14,000 patients at five large transplant centers will be included. The goal is to see if these changes lead to more p…

This study looks at a rare but serious condition called calciphylaxis, where small blood vessels in the skin harden, often leading to death. Researchers will compare 860 adults with chronic kidney disease—some who have calciphylaxis and some who don't—to find clues about what cau…

This pilot study tests whether adjusting magnesium levels in dialysis fluid can reduce harmful blood cell activation during treatment. Fifteen adults with kidney failure will try three different dialysis fluid recipes over six weeks. Researchers will measure blood cell counts and…