END-STAGE RENAL DISEASE

This early-phase trial tests whether giving kidney transplant recipients a special infusion of their donor's light-treated cells, followed by regular light therapy sessions, can safely reduce the risk of organ rejection. About 24 adults receiving a first kidney transplant from a …

This early-stage study tests whether bupropion, a medicine used for smoking cessation and depression, can reduce severe tiredness in people with end-stage kidney disease on dialysis. Sixteen participants will take bupropion three times a week for 8 weeks and report their fatigue …

This study looks at whether combining relaxation exercises with listening to a specific chapter of the Quran (Surah Ar-Rahman) can help people on kidney dialysis feel less anxious, sleep better, and improve their vital signs. 76 adults with advanced kidney disease who are on regu…

This study tests whether adding levocarnitine (a substance often low in dialysis patients) to standard care can reduce the amount of anemia medication needed. About 94 adults on long-term dialysis will receive either levocarnitine injections or usual care alone for 6 months. The …

This study tests if simple eye exercises done during dialysis sessions can help kidney patients improve their balance and reduce their risk of falling. The study will include 30 adults on dialysis. Researchers will check if the exercises are safe and easy to do, and if they show …

This study looks at whether doing joint range-of-motion exercises and Benson relaxation techniques during dialysis can improve how well the treatment works, help patients follow their care plan, and boost quality of life. About 72 adults on long-term hemodialysis will take part. …

This study tests a new wearable device that records sounds from blood vessels used for dialysis. Six adults on hemodialysis will wear the device once a week for 8 weeks to see if it can monitor blood flow as well as a standard stethoscope. The goal is to gather information for fu…

This study will check if men and women on hemodialysis have different balance abilities. About 155 adults aged 20-60 who have been on dialysis for at least a year will do simple walking and sitting tests. The goal is to understand if gender plays a role in balance problems, which…

This study looks at two standard methods of stitching the kidney artery during a living donor kidney transplant: interrupted stitches and continuous stitches. Researchers will review past cases and follow 70 new adult patients for three months after surgery. The goal is to see wh…

This study explores how Black and Caucasian patients with kidney disease communicate with their transplant doctors during evaluation visits. Researchers will record these conversations and survey patients to find out which communication styles lead to more living donor referrals …

This study looks at how often dialysis patients have heart problems caused by tiny blood vessels not working properly. About 30 adults on dialysis for at least 6 months will get a special heart test during a routine procedure. The goal is to learn more about this hidden heart con…

This study tests whether educational videos and text messages can help people with kidney failure learn about and pursue living-donor transplants. About 430 adults waiting for a kidney will be randomly assigned to get the digital tools with or without a human guide. Researchers w…

This study will collect data from 300 kidney transplant patients across Germany to see if machine perfusion parameters (like flow and resistance) can predict how well a donated kidney will work after transplant. The focus is on kidneys from older or higher-risk donors. The goal i…