DIARRHEA

This study tested whether adding calcium to standard oral rehydration solution (ORS) helps adults with severe watery diarrhea, including cholera, recover faster. 396 adults aged 18-60 with acute diarrhea were randomly assigned to receive either calcium-enriched ORS or standard OR…

This study tested whether training local health workers in remote Indian villages could lower death rates among adults aged 16-60. Over 72,000 people from 80 villages took part. The trained workers provided education, treatment, and referrals for conditions like high blood pressu…

This early-stage trial tested a combination of two chemotherapy drugs (irinotecan and temozolomide) plus an antibiotic (cefixime) in 30 children whose high-risk neuroblastoma had come back or not responded to treatment. The main goal was to find the safest dose of oral irinotecan…

This study tested whether a low-cost food storage cabinet called a "meatsafe" could reduce diarrhea in children aged 6 to 24 months in low-income areas of Dhaka, Bangladesh. Researchers compared households that received the cabinet and food safety education with those that did no…

This study tested a drug called isatuximab in 43 people with AL amyloidosis whose disease came back or didn't respond to prior treatments. AL amyloidosis is a rare condition where abnormal proteins build up in organs. Isatuximab is a lab-made antibody that helps the immune system…

This study looked at whether different types of water filters can help prevent diarrhea and other waterborne illnesses in Ciudad Victoria, Mexico. Nearly 10,000 households took part, reporting their health before and after getting a filter. The goal was to see if cleaner drinking…

This study tested whether an oral tablet called Travelan (IMM-124E) can protect healthy adults from getting moderate-to-severe diarrhea caused by a common bacteria (ETEC) that causes traveler's diarrhea. Sixty volunteers were given either Travelan or a placebo and then exposed to…

This study tested whether ondansetron, a common anti-nausea medication, helps children aged 2 to 20 better tolerate the bowel preparation needed before a colonoscopy. The goal was to see if it improves bowel cleanliness and reduces discomfort like pain, bloating, nausea, and vomi…

This study tested whether colesevelam, a medicine used for high cholesterol, could safely reduce diarrhea in people with multiple myeloma who take lenalidomide. 25 participants took colesevelam for 4 weeks. The goal was to see if their diarrhea improved to a mild level or better.

This study looked at whether low vitamin C levels make children aged 2 to 5 more likely to get diarrhea. Researchers compared vitamin C in the blood of children with diarrhea to healthy children of the same age and sex in France, Africa, and South America. The goal is to understa…