DIARRHEA

This study tested whether a daily dose of Travelan (IMM-124E) tablets could prevent moderate-to-severe diarrhea in healthy adults deliberately infected with ETEC bacteria, a common cause of travelers' diarrhea. Sixty-three volunteers took either Travelan or a placebo for 7 days. …

This early-phase study tested a combination of three oral drugs (irinotecan, temozolomide, and cefixime) in 30 children whose high-risk neuroblastoma had come back or not responded to standard treatment. The goal was to find the safest dose of irinotecan when given with the other…

This study tested whether an oral rehydration solution (ORS) with added calcium works better than standard ORS for adults with severe watery diarrhea, including cholera. Researchers measured stool output, diarrhea duration, and other symptoms in 396 adults. The goal is to find a …

This large study in rural India trained village health workers to diagnose and treat common illnesses like high blood pressure, diarrhea, pneumonia, malaria, asthma, and COPD. Over 72,000 adults aged 16-60 from 80 tribal villages took part. The goal was to reduce deaths by at lea…

This study tested whether a low-cost food storage cabinet called a "meatsafe" could reduce diarrhea in children aged 6 to 24 months in low-income areas of Dhaka, Bangladesh. Researchers compared households that received the cabinet and food safety education to those that did not.…

This phase II trial tested the drug isatuximab in 43 patients with AL amyloidosis that had come back or stopped responding to treatment. Isatuximab is a monoclonal antibody that may help stop abnormal protein buildup. The study measured how well the drug reduced disease markers a…

This study tested three types of Sawyer water filters in nearly 10,000 households in Ciudad Victoria, Mexico. The goal was to see if using these filters reduces diarrhea and other waterborne illnesses. Researchers tracked self-reported health changes over time after giving househ…

This study tested health and wellness products to see if they could improve common stomach issues like gas, bloating, diarrhea, and constipation. About 500 adults from across the U.S. took part. Participants took either the product or a placebo (a dummy pill) and reported their s…

This study tested whether colesevelam, a drug used for high cholesterol, can safely reduce diarrhea in people with multiple myeloma who take lenalidomide. 25 participants received colesevelam for 4 weeks. The goal was to see if diarrhea improved to a mild level or better. The stu…

This pilot study tested whether giving ondansetron (Zofran) before drinking bowel-cleansing liquid helps children have a cleaner colon and feel less sick. 41 kids aged 2 to 20 took either ondansetron or a placebo before their colonoscopy. The study measured bowel cleanliness and …

This study looked at how chemotherapy affects the gut microbiome in 40 people with non-Hodgkin's lymphoma. Researchers collected stool samples to analyze changes in gut bacteria after treatment. The goal was to better understand why chemotherapy causes digestive problems like dia…

This study looked at 30 adults with Alpha-Gal syndrome, a condition where eating red meat causes allergic reactions. Participants ate cooked ground pork with or without a sugar called alpha-gal, then researchers checked for allergic reactions, gut symptoms, and changes in immune …

This study examined 288 children aged 2 to 5 in France, Africa, and South America to see if low vitamin C levels are more common in those with diarrhea. Researchers compared vitamin C in the blood of children with diarrhea to healthy children of the same age and sex. The goal is …