DIARRHEA

This Phase 2 trial tested whether the antibody drug isatuximab could help control AL amyloidosis in patients whose disease had returned or didn't respond to prior treatments. The study enrolled 43 adults with confirmed organ damage from this rare protein disorder. Participants re…

This study tested whether adding calcium to standard oral rehydration solution (ORS) could reduce the severity and duration of acute watery diarrhea in adults. Researchers compared the new calcium-enhanced ORS against the standard WHO formula in 396 adults with diarrhea in Bangla…

This large, long-term study tested whether trained village health workers could reduce deaths among working-age adults (16-60 years) in remote tribal villages in India. Over 72,000 participants were involved. The program provided education, basic treatment for common diseases lik…

This study tested if a product called Travelan could prevent moderate-to-severe diarrhea in healthy adults. Sixty volunteers took either Travelan or a placebo (inactive look-alike) for a week and were then intentionally given bacteria that commonly cause traveler's diarrhea. Rese…

This study tested three types of Sawyer water filters in nearly 10,000 households in Mexico to see which was best at preventing diarrhea and other illnesses from dirty water. Researchers tracked how often families got sick and measured the economic impact of having clean water. T…

This study tested whether a low-cost, mesh-covered food storage cabinet (called a 'meatsafe') could keep children's food cleaner and reduce diarrhea. Researchers gave the cabinets and food safety tips to some families in low-income neighborhoods of Dhaka, Bangladesh, and compared…

This study tested if a drug called colesevelam could safely reduce diarrhea caused by lenalidomide, a common maintenance therapy for multiple myeloma. It involved 25 adult patients with myeloma who were experiencing this specific side effect. The main goal was to see if their dia…

This study tested if adding an anti-nausea medicine (ondansetron) to the standard laxative drink could make the colonoscopy preparation process easier for children and teens. The goal was to see if reducing nausea and discomfort helped patients finish the prep drink, leading to a…

This study aimed to understand if a lack of vitamin C makes young children more likely to get diarrhea, a major cause of death in kids under five. Researchers compared vitamin levels in the blood of children with and without diarrhea across several countries. The goal was to gath…