DIARRHEA

This study tests whether Water Safety Plans—a set of management steps to keep drinking water safe from source to tap—can improve water quality and reduce diarrhea in rural Ghana. About 4,500 people from communities served by private water suppliers will be involved. Researchers w…

This study tests whether giving probiotics (Bacillus clausii) to critically ill adults can reduce serious infections like pneumonia and bloodstream infections. One hundred ICU patients will receive either the probiotic or a sugar pill, and researchers will track infection rates a…

This study tests whether replacing dirt floors with concrete in rural Bangladeshi homes can reduce infections in children. About 800 pregnant women and their future babies will take part, with children checked for parasites and diarrhea up to age 2. If concrete floors lower infec…

This study tests whether a probiotic called Bifidobacterium longum BBH016 can improve lower gut symptoms like abdominal pain, diarrhea, and bloating. 88 adults with these symptoms but no constipation will take either the probiotic or a placebo capsule twice daily for 8 weeks. Res…

This study tests whether fecal microbiota transplantation (FMT) – giving healthy donor stool in capsules – can safely reduce chronic diarrhea in people with systemic sclerosis. Twenty adults with scleroderma and persistent diarrhea will receive either FMT or a placebo. The main g…

This study looks at whether using a UV light filter on private well water can lower the chance of stomach infections in children under 5. About 900 families in Pennsylvania and New Jersey will either get a working UV filter or a fake one. Researchers will track how often kids get…

This study looks at how diet, genetics, and gut bacteria work together to cause digestive problems like IBS, IBD, and celiac disease. Researchers will follow about 4,000 adults with and without these conditions to find patterns. The goal is to understand why some people get sick …