Could a cholera vaccine stop Kids' diarrhea?
NCT ID NCT07300462
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This large study tests whether an oral cholera vaccine can also protect children aged 2 to 14 from infectious diarrhea caused by other germs. 6,000 healthy kids will get either the vaccine or a placebo. The goal is to see if the vaccine lowers the number of diarrhea cases, building on earlier hints of broader protection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oral recombinant subunit B/bacterial cholera vaccine (enteric-coated capsules)
What this could lead to
If successful, this vaccine could help prevent common infectious diarrhea in children, reducing illness and antibiotic use.
What could go wrong
This is a large phase 4 trial, but the vaccine is being tested for a new use (non-cholera diarrhea). It may not work as well in real-world conditions, and side effects are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Anhui Provincial Center for Disease Control and Prevention
Hefei, Anhui, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hubei Provincial Center for Disease Control and Prevention
Wuhan, Hubei, China
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiangsu Provincial Center for Disease Control and Prevention
Nanjing, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Institute for Communicable Disease Control and Prevention, China
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shandong Provincial Center for Disease Control and Prevention
Jinan, Shandong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••