DIARRHEA

This large study tests whether an oral cholera vaccine can also protect children aged 2 to 14 from infectious diarrhea caused by other germs. 6,000 healthy kids will get either the vaccine or a placebo. The goal is to see if the vaccine lowers the number of diarrhea cases, buildi…

This study tests whether an artificial intelligence (AI) tool can help doctors spot precancerous growths in the upper part of the colon during a colonoscopy. About 1,200 people with symptoms like belly pain, constipation, or black stools will take part. The goal is to see if usin…

This study tests a device that automatically adds chlorine to community water systems in rural Nigeria, without needing electricity or daily effort. The goal is to see if it makes drinking water cleaner and reduces diarrhea, especially in children under five. About 2,655 adults a…

This early-phase study tests whether a mixture of 157 live bacteria from healthy stool, called MITI 001, is safe for people with diarrhea-predominant irritable bowel syndrome (IBS-D). The goal is to restore healthy gut function and ease symptoms. Only 13 adults with specific sign…

This study will follow 100 people with severe obesity who are starting a GLP-1 drug (like Ozempic or Wegovy) to see if it causes new anal or rectal problems within the first 3 months. Participants will have a check-up before starting the drug and again after 3 months to look for …

This study in Côte d'Ivoire tests whether giving mothers a cash reward for breastfeeding until their child is 24 months old increases breastfeeding rates and improves child and maternal health. About 1,040 mothers will either receive the cash incentive or just educational materia…

This study looks at why some breast cancer patients get diarrhea from the drug pyrotinib while others don't. Researchers will compare the gut bacteria of 60 patients who develop diarrhea with those who don't. They hope to find specific bacteria that protect against this side effe…