Could a simple tablet stop Travelers' diarrhea before it starts?
NCT ID NCT05933525
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a daily dose of Travelan (IMM-124E) tablets could prevent moderate-to-severe diarrhea in healthy adults deliberately infected with ETEC bacteria, a common cause of travelers' diarrhea. Sixty-three volunteers took either Travelan or a placebo for 7 days. Researchers measured how many people developed severe diarrhea and how much stool they produced. The goal is to find a simple, safe way to protect travelers from this unpleasant illness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Travelan (IMM-124E) tablets
What this could lead to
If it works, this could provide a simple daily pill to prevent travelers' diarrhea caused by ETEC bacteria.
What could go wrong
This is a small Phase 2 trial with only 63 participants, so results may not apply to everyone. The study is completed but not yet published, so we don't know if it worked.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Pharmaron Clinical Pharmacology Center
Baltimore, Maryland, 21201, United States