DIABETE MELLITUS

This study is testing the safety of the FreeStyle Libre 2, a device that continuously checks blood sugar levels, in 550 children and young adults aged 4 to 30 with type 1 or type 2 diabetes. The goal is to see if using this monitor reduces severe low blood sugar events that need …

This study compares two wound treatments for people with diabetes who have severe foot wounds after leg artery surgery. One group gets standard vacuum therapy, the other gets the same therapy plus a silver nanoparticle spray applied to the wound. The goal is to see which approach…

This study tests whether linaclotide (Linzess) can improve bowel movement frequency in people with type 2 diabetes who have chronic constipation. About 23 participants will receive either the drug or a placebo for two weeks, then switch after a break. The goal is to see if the dr…

This study compares total intravenous anesthesia (TIVA) to balanced anesthesia (using inhaled gas) in 60 diabetic patients undergoing video-assisted chest surgery. The goal is to see which method better controls blood sugar and reduces stress during surgery. Researchers will also…

This study looks at whether referring lonely older adults with diabetes to a social worker can help them feel less lonely and improve their blood sugar control. About 90 seniors will either meet with a social worker or continue their usual care. Researchers will check loneliness …

This study aimed to see if making physical activity into a game could help older hospital patients move more. Participants would have received daily text messages, set step goals, earned points, and worn a Fitbit to track their steps. The study was withdrawn before any patients w…

This study tests whether a gel made from a patient's own blood platelets can help diabetic individuals heal faster after tooth removal. Twelve adults with diabetes who need two similar-sized tooth extractions will receive the gel in one socket and standard care in the other. Rese…

This study tests two types of nerve stretches—active (patient-controlled) and passive (therapist-applied)—to see which better reduces burning pain, improves muscle strength, and increases joint movement in people with diabetic neuropathy. Sixty adults aged 40 to 65 with diabetes …

This study looks at blood markers that might predict deep wound infections after heart surgery. Researchers will track 30 patients to see if certain inflammatory biomarkers can help identify those at risk. The goal is to create a prevention plan to reduce these serious infections…

This study looks at people with rare adrenal tumors (pheochromocytomas and paragangliomas) that do not produce excess hormones. Researchers want to see if these 'silent' tumors still cause heart problems, blood pressure changes, or metabolic issues like diabetes and high choleste…