DIABETE MELLITUS

This study compares two wound treatments for people with diabetes who have serious foot wounds after leg artery surgery. One group gets standard vacuum therapy, the other gets the same therapy plus a silver nanoparticle spray. The goal is to see which approach helps wounds close …

This study is testing the safety of the FreeStyle Libre 2, a flash glucose monitoring system, in 550 children and young adults aged 4 to 30 with type 1 or type 2 diabetes. The goal is to see if using this device lowers the rate of severe low blood sugar events that need medical h…

This study tests whether a gel made from a patient's own platelets can speed up healing and reduce pain after tooth removal in people with diabetes. Twelve diabetic adults needing two similar tooth extractions will receive the gel in one socket and standard care in the other. The…

This study tests whether linaclotide, a drug for constipation, works better than a placebo in people with type 2 diabetes who have chronic constipation. About 23 participants will receive either the active drug or placebo for two weeks, then switch after a two-week break. The mai…

This study looks at whether referring lonely older adults with diabetes to a social worker can help them feel less lonely and improve their blood sugar control (A1C). About 90 seniors will be randomly assigned to either meet with a social worker or continue their usual care. Rese…

This study tests two types of nerve-gliding exercises—active (done by the patient) and passive (done by a therapist)—in 60 adults aged 40–65 with diabetic neuropathy. The goal is to see which method better reduces burning pain, improves muscle strength, and increases joint moveme…

This study compares two anesthesia methods—total intravenous anesthesia (TIVA) and balanced anesthesia (using inhaled gas)—in 60 diabetic adults having video-assisted chest surgery. The goal is to see which method better controls blood sugar and reduces stress during surgery. Res…

This study aimed to see if using wearable step counters and smartphone games could encourage hospital patients with heart conditions to walk more. It planned to enroll adults aged 50 and older admitted to medicine or cardiology floors. However, the study was withdrawn before any …

This study looks at whether certain substances in the blood can help predict deep wound infections after open-heart surgery. Researchers will track 30 patients who already have a deep sternal wound infection to see how their blood markers change before and after surgery. The goal…

This study looks at heart and metabolic problems in people with biochemically silent pheochromocytomas and paragangliomas (rare adrenal tumors that don't produce excess hormones). Researchers will measure blood pressure, heart function, and metabolic markers before and after surg…