DIABETE MELLITUS

This study tests a new medicine called DA-5218 for people with type 2 diabetes whose blood sugar is not well controlled with metformin alone. About 238 adults will receive either DA-5218 or an active comparator to see how well it lowers HbA1c (a measure of blood sugar over time) …

This early-stage study tests a new treatment called SR-02 for adults with type 1 diabetes who have severe low blood sugar episodes. The treatment involves implanting insulin-producing cells into the belly lining. Participants will need to take lifelong anti-rejection drugs. The g…

This study tests a new procedure called duodenal recellularization therapy for people recently diagnosed with type 2 diabetes. The goal is to see if it can help control blood sugar without needing diabetes medications. The study will include 40 participants and follow them for 24…

This study tests a digital tool called "Smart Family Doctor" that uses artificial intelligence to help patients manage high blood pressure, diabetes, and high cholesterol after heart surgery or stenting. About 951 adults who have had bypass surgery or a stent placed will use the …

This study tests whether adding a new drug called DA-2811 to standard diabetes medications helps lower blood sugar more effectively in people with type 2 diabetes. About 288 adults with poorly controlled diabetes will receive either DA-2811 or a placebo alongside their usual trea…

This study tests whether a dietary supplement called tributyrin can improve blood sugar control, reduce inflammation, and lower heart disease risk in people with type 2 diabetes. About 60 adults with diabetes and elevated heart risk will receive either tributyrin plus their usual…

This study tests whether a common diabetes drug (a DPP4 inhibitor) can help prevent or improve memory and thinking problems that often occur after a mild stroke. Researchers will give the drug or a placebo for 180 days to 312 adults aged 40-75 who have had a mild stroke and have …

This study compares silicone pads to felted foam for reducing pressure under the foot in people with diabetes and nerve damage who are at high risk of foot ulcers. About 80 participants will wear each type of pad, and researchers will measure how well they lower pressure and how …

This study tests whether regular phone calls from a nurse can help adults with diabetes in Ethiopia improve their blood sugar control, take their medication as prescribed, and learn more about managing their condition. About 320 participants will either receive usual care or also…

This study is testing whether a 12-week education program delivered through WhatsApp, which involves a family member, can help people with type 2 diabetes better manage their condition. The program sends educational materials and quizzes to both the person with diabetes and their…

This study tests a new way to detect early damage in the feet of people with diabetes. By measuring how the skin on the bottom of the foot responds to pressure, researchers hope to find signs of trouble before ulcers form. The study will include 200 people, both with and without …

This study looks at better ways to diagnose nerve damage caused by diabetes. Researchers will use nerve tests and ultrasound in 75 adults with diabetes and healthy volunteers. The goal is to find nerve problems earlier so patients can get the right care sooner.

This early-stage trial tests whether giving a salbutamol inhaler during surgery can prevent lung collapse (atelectasis) in diabetic patients. About 80 adults aged 18-70 undergoing chest, belly, or spine surgery will be studied. The goal is to see if this common asthma drug can re…

This study tests a simple color rotation training technique to help people with diabetes better manage their insulin injections. Researchers will teach 112 adults who use insulin four times a day a color-based system to organize their shots. The goal is to see if this method impr…

This study tests a special colonoscopy preparation for people with diabetes. The goal is to see if a simpler diet and same-day prep can reduce dangerous low blood sugar events and still clean the bowel well. About 40 adults with diabetes will be assigned to either the new protoco…

This study aims to see if routine blood tests can help predict how severe a heart attack is and what the future health outcomes might be, especially for people with diabetes. Researchers will follow 1,000 patients having emergency heart artery opening procedures. The goal is to f…

This study will track menstrual cycles in 110 teenage girls (ages 10-18) with and without diabetes to see how diabetes affects period regularity. Researchers will also check if blood sugar control and body weight are linked to menstrual problems. The goal is to better understand …

This study will measure levels of a specific thyroid antibody (anti-thyroglobulin) in 112 adults with diabetes. The goal is to better understand how often diabetes and autoimmune thyroid problems occur together. Participants will give a blood sample, and those with a history of t…

This study will check the 10-year heart disease risk in 238 adults with type 2 diabetes, using a standard WHO risk chart. It will then see if simple belly fat measurements (like waist-based scores) match that risk. No treatment is given—only observation and measurement.

This study aims to create an AI-based system that helps people with diabetes avoid repeat foot ulcers. Researchers will follow 200 adults whose foot ulcers have healed, using a home monitoring tool and personalized follow-up plans to catch early warning signs. The goal is to redu…

This early-stage study will give 100 healthy volunteers one of three statins (atorvastatin, rosuvastatin, or simvastatin) for two days to see how their blood sugar, insulin, and C-peptide levels change. The goal is to understand if these cholesterol-lowering drugs can temporarily…