CONGENITAL HEART DISEASE

This study is testing a new adjustable heart valve for children aged 18 months to 16 years who need surgery to replace a faulty pulmonary valve. The valve can be expanded before or after surgery to better fit the child's size and potentially accommodate their growth, which may re…

This study is testing a new two-part device designed to fix leaky or narrowed pulmonary heart valves in people born with certain heart defects. The device is implanted using a catheter through blood vessels, avoiding open-heart surgery. Researchers want to see if it's safe and ef…

This study is testing if adding nitric oxide gas to the heart-lung machine during surgery helps protect babies' brains and kidneys. It involves infants under 1 year old who need surgery to fix a congenital heart defect. Researchers will measure specific proteins in the blood befo…

This study is testing a new driving system for a heart pump designed to help children with severe heart failure. The pump supports the child's heart while they wait for a transplant. Researchers will monitor how well the new system works and how safe it is for up to 40 children w…

This study is monitoring how well a recently approved replacement heart valve works in everyday medical practice. It follows 150 patients born with specific heart defects who have received this valve. The main goal is to check if the valve is still working properly and hasn't nee…

This study is evaluating a new heart valve implant called the Harmony TPV. It is for people born with heart defects that cause severe leakage of their pulmonary valve. Doctors implant the new valve using a catheter through a blood vessel, avoiding open-heart surgery, to see if it…

This study is collecting real-world safety information about rivaroxaban, a blood-thinning medication, in children who have undergone Fontan heart surgery. Researchers are monitoring 61 pediatric patients to better understand the risks of major and minor bleeding events during tr…

This study is testing whether a special adhesive heart monitor patch called Zio® can be worn by children for up to 14 days. Researchers want to see if the patch sticks well to a child's skin and provides clear heart rhythm readings. The study involves 36 children between 1 and 17…

This study is testing if special, low-energy MRI settings can safely allow doctors to use standard guidewires during a heart catheterization procedure. Guidewires help steer the catheter but are usually unsafe in an MRI because they can heat up. Researchers want to see if this ne…

This study is testing a web-based decision aid designed to help parents who must make urgent, life-altering choices for a fetus or newborn diagnosed with a severe, life-threatening heart defect. Researchers are comparing parents who use the tool to those who don't, to see if it r…

This study aims to see if blood tests taken during and after pregnancy can predict future heart problems in women who were born with a heart condition. Researchers will follow 100 pregnant women with congenital heart disease to see if changes in these blood markers over time give…