Could a common heart drug fix a rare surgery complication in kids?

NCT ID NCT06833320

Terminated Disease control Sponsor: June Wu Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether propranolol, a drug often used for high blood pressure, can safely treat chylothorax—a buildup of lymphatic fluid—in children after open heart surgery. About 50 children aged 7 days to 18 years with congenital heart disease will receive either propranolol or a placebo. The goal is to see if the drug helps resolve the fluid leak faster and to identify which patients benefit most.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propranolol
What this could lead to: If it works, this could provide a safe, non-surgical treatment for a serious complication after heart surgery in children.
What could go wrong: This is an early-phase trial with only 50 participants, and it is currently suspended. Not all patients responded in earlier studies, and side effects like low blood pressure or low blood sugar are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chylothorax congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHYLOTHORAX CONGENITAL HEART DISEASE OPEN HEART SURGERY POSTOPERATIVE CHYLOTHORAX

Contacts and locations

Locations

Columbia University Irving Medical Center/NewYork-Presbyterian

New York, New York, 10032, United States

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