Blood protein test could predict Post-Surgery risks in kids with heart defects

NCT ID NCT06642662

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study at Boston Children's Hospital will test whether measuring thousands of proteins in a few drops of blood can predict which children with congenital heart disease will have serious complications after heart surgery. Researchers will collect blood samples from 60 children before and after surgery and combine protein profiles with clinical data to build a risk-prediction model. The goal is to move from a one-size-fits-all approach to personalized care in the Cardiac ICU.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a blood test that helps doctors predict which children are at highest risk for complications after heart surgery, allowing earlier and more personalized treatment.

What could go wrong

This is a small, early feasibility study (60 participants) that is only looking for patterns in proteins, not testing any treatment. The findings may not lead to a usable prediction tool or improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital heart disease hypoplastic left heart syndrome transposition of the great arteries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States