COLORECTAL NEOPLASMS
Clinical trials for COLORECTAL NEOPLASMS explained in plain language.
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New cancer drug shows promise in advanced tumors
Disease control OngoingThis study is testing whether an experimental drug called tisotumab vedotin, given alone or with other cancer drugs, can help control advanced solid tumors. It enrolled 352 people with advanced colorectal, lung, pancreatic, or head and neck cancers that had stopped responding to …
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug combo tested for Tough-to-Treat cancers
Disease control OngoingThis study is testing a new drug called E7386 in combination with other cancer medications for people with advanced solid tumors, including endometrial, liver, and colorectal cancers. The main goals are to find the safest and most effective dose and to see how well the drug combi…
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Eisai Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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First human tests begin for experimental cancer drug targeting multiple tumor types
Disease control OngoingThis early-stage study is testing a new drug called PF-08046052/SGN-EGFRd2 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goal is to find the safest dose and understand side effects in 65 participants with specific cancers includin…
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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First human test of Pfizer's new cancer pill targets tough tumors
Disease control OngoingThis is an early safety study for a new oral medicine, PF-07985045, designed for people with advanced solid tumors that have a specific KRAS gene mutation. The study will test the medicine by itself and combined with other cancer treatments to find a safe dose and see how the bod…
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New 'Smart Bomb' drug enters human testing for Tough-to-Treat cancers
Disease control OngoingThis is an early-stage study testing a new experimental drug called SGN-MesoC2 in people with advanced solid tumors that have come back or stopped responding to standard treatments. The main goal is to find a safe dose and see how the body handles the drug. The drug is designed t…
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Can a special diet after your colonoscopy keep polyps away?
Disease control ENROLLING_BY_INVITATIONThis study is testing whether eating a specific high-fiber, plant-based Mediterranean diet for two weeks after a colonoscopy can improve gut health. Researchers will enroll 30 people with a history of colon polyps to see if the diet reduces inflammation, changes gut bacteria, and…
Matched conditions: COLORECTAL NEOPLASMS
Phase: NA • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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First human test of experimental cancer drug begins
Disease control OngoingThis is an early-stage study to test the safety and find the right dose of a new drug called PF-08046049/SGN-BB228. It is for adults with advanced solid tumors, including melanoma, lung, colorectal, pancreatic cancer, or mesothelioma, that have stopped responding to standard trea…
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for tough cancers: experimental combo targets key mutation
Disease control OngoingThis study is testing new drug combinations for people with advanced solid tumors that have a specific genetic change called KRAS G12C. It focuses on patients with non-small cell lung cancer or colorectal cancer who have already tried standard treatments. The main goals are to fi…
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Three-Drug attack on tough cancers shows promise
Disease control OngoingThis study is testing whether combining two or three different cancer drugs works better than single drugs to control advanced cancers that have come back or spread. It is for adults with advanced ovarian, breast, lung, prostate, or colorectal cancer who have few other treatment …
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC
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Can your diet stop cancer? new study tests three eating plans for High-Risk adults
Prevention OngoingThis study is testing three different healthy eating approaches to see which best helps overweight adults at risk for colorectal cancer improve their diet and potentially lose weight. 240 participants will follow one of the eating plans for 12 months, with some groups getting ext…
Matched conditions: COLORECTAL NEOPLASMS
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Mar 23, 2026 15:17 UTC
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Can a tailored fitness plan ease cancer recovery for black survivors?
Symptom relief OngoingThis study is testing whether a physical activity program, co-created with the community, is practical and helpful for Black colorectal cancer survivors. Researchers are measuring if the program improves quality of life, reduces symptoms like fatigue and pain, and increases daily…
Matched conditions: COLORECTAL NEOPLASMS
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Phone-Guided home workouts aim to boost recovery for elderly cancer patients
Symptom relief OngoingThis study is testing whether a personalized, home-based exercise program can help older adults recover better from colorectal cancer surgery. The program focuses on strength, balance, and breathing, with weekly phone check-ins from an exercise specialist. Researchers want to see…
Matched conditions: COLORECTAL NEOPLASMS
Phase: NA • Sponsor: Hospital General Universitario Gregorio Marañon • Aim: Symptom relief
Last updated Mar 19, 2026 14:55 UTC
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An open-label phase 1 study of E7386 in subjects with advanced solid tumor including colorectal cancer
OngoingThis study will be conducted to assess the safety and tolerability of E7386 in participants with solid tumor including CRC.
Matched conditions: COLORECTAL NEOPLASMS
Phase: PHASE1 • Sponsor: Eisai Co., Ltd.
Last updated Mar 02, 2026 15:24 UTC