COLORECTAL NEOPLASMS

This trial is testing if two already-approved cancer drugs, dabrafenib and trametinib, can help patients with rare cancers or common cancers that have a rare, specific genetic change called a BRAF V600 mutation. The drugs are already used for some cancers like melanoma, but resea…

This study compares two ways to perform surgery for right-sided colon cancer. It aims to see if a 'keyhole' (laparoscopic) approach leads to less blood loss, fewer complications, and a shorter hospital stay than traditional open surgery, while still removing the cancer effectivel…

This study is testing whether an artificial intelligence (AI) system can help doctors find more polyps and early cancers during a routine colonoscopy. About 3,300 people will be randomly assigned to have their colonoscopy done with or without the AI assistant. The goal is to see …

This study is comparing two advanced camera techniques used during routine colon cancer screening for people with inflammatory bowel disease (IBD). One method uses a special dye sprayed in the colon, while the newer method uses special camera light filters without any dye. Resear…

This study tests whether a new program using an AI chatbot and coordinated doctor follow-ups can get more people to complete a colonoscopy for cancer screening. It will involve 400 people in China aged 40-64 who are at higher risk for colorectal cancer. The goal is to see if this…

This study is testing if a more personalized screening plan can better prevent colon cancer in people at very high risk. It compares the standard approach (a colonoscopy every 3 years) to a new plan using a simple annual stool test to catch problems earlier. The goal is to see if…

This study tests whether virtual reality health education can help colorectal cancer survivors improve their quality of life and adopt healthier habits after surgery. Researchers will enroll 174 patients who have completed cancer surgery and randomly assign them to either receive…

This study aims to collect blood samples from 1,000 patients to see if a 'liquid biopsy' blood test can better predict which small colon growths are cancerous and which are not. The goal is to help doctors decide if a patient needs surgery or can be safely monitored, potentially …