COLON ADENOCARCINOMA
Clinical trials for COLON ADENOCARCINOMA explained in plain language.
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New study may let some colon cancer patients skip major surgery
Disease control Recruiting nowThis study is for people with early-stage colon cancer (stage I) who currently need a colectomy to remove part of the colon. The SENTRY trial tests a less invasive option: removing only the tumor and nearby lymph nodes using a camera and a special dye. The goal is to see if this …
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Meander Medical Center • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New hope for hard-to-treat colon cancer: targeted combo enters phase 3 trial
Disease control Recruiting nowThis study tests whether adding the targeted drugs MK-1084 and cetuximab to standard chemotherapy (mFOLFOX6) helps people with a specific genetic mutation (KRAS G12C) in advanced colorectal cancer live longer without the cancer growing. About 477 participants will be randomly ass…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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DNA blood test guides next move against stubborn colon cancer
Disease control Recruiting nowThis early-phase study tests whether a combination of two chemotherapy drugs (trifluridine/tipiracil and irinotecan) can clear leftover cancer cells in people with colon cancer whose blood still shows cancer DNA after standard treatment. About 22 adults with stage II–IV colon can…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Liver transplant offers new hope for advanced colon cancer patients
Disease control Recruiting nowThis study tests whether a liver transplant from a living donor can help people with colon cancer that has spread only to the liver and cannot be removed by surgery. About 25 adults with this condition will receive a transplant and be compared to similar patients who had chemothe…
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Azienda Ospedaliero-Universitaria di Modena • Aim: Disease control
Last updated May 07, 2026 18:38 UTC
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New combo aims to shrink colon tumors before surgery
Disease control Recruiting nowThis study tests whether adding a drug called tolecizumab to standard chemotherapy and immunotherapy can better shrink advanced colon cancer before surgery. About 106 adults with a specific type of colon cancer will be randomly assigned to receive the combination or standard trea…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated May 01, 2026 15:57 UTC