Blood test may help tailor chemo for colon cancer patients with hidden disease

NCT ID NCT04920032

First seen Apr 21, 2026 · Last updated Jun 16, 2026 · Updated 11 times

Summary

This early-stage study tests whether a blood test that detects tiny amounts of cancer DNA (ctDNA) can help doctors decide when to switch chemotherapy for colon cancer patients who still have signs of disease after surgery. About 22 adults with stage II–IV colon cancer will receive a combination of two chemotherapy drugs (trifluridine/tipiracil and irinotecan) if their ctDNA test remains positive. The main goal is to see if this approach can clear the ctDNA, indicating the treatment is working.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Chao Family Comprehensive Cancer Center, University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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