Blood test guides next move against stubborn colon cancer

NCT ID NCT04920032

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with colon cancer who still have signs of cancer in their blood (ctDNA positive) after surgery and standard chemotherapy. It tests whether switching to a combination of two drugs (trifluridine/tipiracil and irinotecan) can clear those remaining cancer cells. About 22 adults with stage II–IV colon cancer will take part. The goal is to see if this approach can control the disease, not cure it, as ongoing monitoring and treatment may be needed.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Chao Family Comprehensive Cancer Center, University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Email: •••••@•••••

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