COLON ADENOCARCINOMA
Clinical trials for COLON ADENOCARCINOMA explained in plain language.
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Blood test may help tailor chemo for colon cancer patients with hidden disease
Disease control Recruiting nowThis early-stage study tests whether a blood test that detects tiny amounts of cancer DNA (ctDNA) can help doctors decide when to switch chemotherapy for colon cancer patients who still have signs of disease after surgery. About 22 adults with stage II–IV colon cancer will receiv…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Jun 17, 2026 00:30 UTC
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New drug cocktail aims to shrink colon tumors before surgery
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug dostarlimab to standard chemotherapy (CAPEOX) works better than chemotherapy alone for a specific type of colon cancer (MMRp/MSS). About 120 people with stage III or T4N0 colon cancer that has not been treated yet will receiv…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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Less cutting, same safety? new trial tests Mini-Surgery for colon cancer
Disease control Recruiting nowThis study tests a less invasive surgery for people with early-stage colon cancer. Instead of removing a large piece of the colon, doctors will remove only the tumor and a few key lymph nodes using a special dye. The goal is to see if this smaller surgery works as well as the sta…
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Meander Medical Center • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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New hope for KRAS-Mutant colon cancer: targeted combo trial launches
Disease control Recruiting nowThis study tests whether adding the targeted drugs calderasib and cetuximab to standard chemotherapy can help people with a specific genetic form of advanced colorectal cancer (KRAS G12C mutation) live longer without their cancer growing. About 477 adults with inoperable or metas…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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New combo aims to boost colon cancer treatment before surgery
Disease control Recruiting nowThis study tests whether adding tolecizumab (a PCSK9 inhibitor) to standard chemoimmunotherapy can better shrink locally advanced colon cancer before surgery. About 106 adults with a specific type of colon cancer will receive either the combo or standard treatment alone. The main…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Living liver donors offer new hope for advanced colon cancer patients
Disease control Recruiting nowThis study tests whether a liver transplant from a living donor can help people with colon cancer that has spread only to the liver and cannot be removed by surgery. About 25 adults will receive a partial liver from a healthy donor. The goal is to see if this approach helps them …
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Azienda Ospedaliero-Universitaria di Modena • Aim: Disease control
Last updated Jun 08, 2026 13:09 UTC