CIRCADIAN RHYTHM

This study tests whether eating meals at times that match your body's internal clock can help people who have had weight-loss surgery keep the weight off and improve their health. About 246 adults who had sleeve gastrectomy at least six months ago will either follow standard diet…

This study tests whether a digital program that combines cognitive behavioral therapy for insomnia with circadian rhythm coaching can prevent depressive symptoms from worsening in college students aged 18-24 who have trouble falling asleep and tend to be night owls. Participants …

This study compares two exercise approaches—short 'exercise snacks' spread throughout the day versus traditional aerobic exercise—in adults with moderate to severe obstructive sleep apnea. Researchers will measure sleep quality, daytime sleepiness, and physical function over 8 we…

This study tests whether doing progressive relaxation exercises at times matched to each patient's natural circadian rhythm can help manage symptoms, improve sleep quality, increase comfort, and boost mental well-being in people receiving hemodialysis. Researchers will enroll 75 …

This study tests whether a drug called esketamine can improve sleep after surgery in postmenopausal women, who often have trouble sleeping. About 164 women having leg fracture surgery will receive esketamine or a placebo during the operation. Researchers will check their sleep qu…

This study looks at whether doing moderate resistance exercises in the morning can improve sleep quality in young adults aged 18-35. Over 8 weeks, 64 participants with different sleep patterns (morning or evening types) will follow an online exercise program. Researchers will mea…

This study looks at how whole-body heat therapy (hyperthermia) changes body temperature, pain sensitivity, and pain during movement in 60 people—half with chronic widespread pain (like fibromyalgia) and half healthy. Participants will receive six heat sessions over three weeks. T…

This study will test a new wearable device that monitors your body's internal clock (circadian rhythm) by tracking signals like heart rate and movement. Researchers will compare the device's readings to standard saliva tests in 30 adults who are either healthy, have sleep apnea, …

This study looks at how losing sleep and having a disrupted body clock (like shift workers) can make the body less responsive to insulin, a key step toward obesity and type 2 diabetes. Researchers will test 48 healthy adults aged 18-45 to see how the timing of the stress hormone …

This pilot study looks at how sleep, physical activity, and meal timing in early pregnancy relate to blood sugar patterns and the risk of gestational diabetes. Researchers will track 140 pregnant women using wearable devices and an AI food-logging app. The goal is to see if real-…

This study looks at whether giving preterm babies their mother's breast milk at the same time of day it was expressed (like night milk at night) helps them sleep better and develop a healthy day-night rhythm. About 200 preterm infants will be split into two groups: one gets milk …

This study looks at how the time of day and the menstrual cycle (specifically low vs. high progesterone phases) affect strength and thinking in female athletes. Thirty women aged 18-30 who train regularly will be tested at 7am, 12pm, and 6pm during two different phases of their c…

This study follows 160 adults in Hong Kong over time to see if disruptions in daily activity and sleep (rest-activity rhythms) can predict who develops major depressive disorder. Participants will wear activity monitors and complete questionnaires about mood and sleep. The goal i…

This study looks at whether exercising at different times of day changes how we feel pain. Fifty-six healthy adults will do a 12-minute high-intensity workout in both the morning and evening. Researchers will measure pain thresholds before and after exercise to see if time of day…

This study looks at whether the natural drop in blood pressure during sleep (called 'dipping') is linked to changes in the heart's electrical activity in people with high blood pressure. Researchers will monitor 140 adults using a 24-hour blood pressure device and compare those w…