CHRONIC KIDNEY DISEASE (CKD)
Clinical trials for CHRONIC KIDNEY DISEASE (CKD) explained in plain language.
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Simple medication check slashes readmission risk for kidney patients?
Disease control CompletedThis study tested whether a thorough medication review at hospital admission and discharge could reduce mistakes and prevent patients with chronic kidney disease from being readmitted within 90 days. Researchers compared 323 patients who received this extra service to a similar g…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New device aims to improve dialysis access for kidney patients
Disease control CompletedThis study tested a new device called FLEX-1 that creates a special blood vessel connection (called an arteriovenous fistula) for people with advanced kidney disease who need dialysis. Sixteen adults with stage 4 or 5 chronic kidney disease took part. The goal was to see if the d…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New device aims to simplify dialysis access for kidney patients
Disease control CompletedThis study tested a new device called FLEX-1 to create a special blood vessel connection (arteriovenous fistula) for dialysis in 17 adults with advanced chronic kidney disease. The goal was to see if the device is safe and works well for hemodialysis. The study focused on complic…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New pill could help dialysis patients control dangerous phosphorus levels
Disease control CompletedThis Phase 3 trial tested a new drug called AP301 in 474 Chinese adults on dialysis who had high phosphorus levels. Participants took AP301, a low dose of AP301, or the standard drug sevelamer carbonate with meals. The main goal was to see how well AP301 lowers phosphorus compare…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: PHASE3 • Sponsor: Alebund Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Breathing workouts boost lung power in young kidney transplant recipients
Symptom relief CompletedThis study tested whether 8 weeks of respiratory muscle training using a special breathing device could improve lung function and muscle strength in 30 children aged 8-18 who had a kidney transplant at least 6 months earlier. The training involved both inspiratory and expiratory …
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: Atlas University • Aim: Symptom relief
Last updated Jun 26, 2026 14:31 UTC
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Hidden patterns: how three chronic diseases often travel together
Knowledge-focused CompletedThis completed observational study looked at 4500 patients admitted to internal medicine wards with heart failure, COPD, or chronic kidney disease. Researchers aimed to identify which other chronic conditions tend to cluster with these diseases, and how those clusters affect pati…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: Fadoi Foundation, Italy • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can a phone coach and doctor registry improve kidney care?
Knowledge-focused CompletedThis study looked at two tools to help people with chronic kidney disease (CKD) stay healthier. One tool gave doctors a registry to track patients, and the other offered phone coaching from a health coach. The goal was to see if these approaches could lower blood pressure and imp…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Study reveals trazodone dosing dangers for seniors with kidney trouble
Knowledge-focused CompletedThis study examined over 31,000 older adults (65+) with chronic kidney disease to see if starting a higher dose of the sleep medication trazodone (75-150 mg/day) leads to more serious events like hospital visits or death within 30 days compared to a lower dose (25-75 mg/day). The…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Higher antidepressant dose may pose risks for seniors with weak kidneys
Knowledge-focused CompletedThis study looked at over 7,000 older adults (65+) with reduced kidney function who started taking the antidepressant citalopram. Researchers compared a 20 mg/day dose to a 10 mg/day dose to see if the higher dose increased the risk of serious events like hospitalization, emergen…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Higher dose of common drug may raise hospital risk for seniors with kidney trouble
Knowledge-focused CompletedThis completed study looked at 1,100 older adults (65+) with advanced chronic kidney disease who started taking pramipexole, a drug for restless legs or Parkinson's. Researchers compared a very low starting dose (0.125 mg/day) to slightly higher doses (0.25 or 0.375 mg/day) to se…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Higher antidepressant dose may raise risks for seniors with weak kidneys
Knowledge-focused CompletedThis completed study looked at nearly 7,000 older adults (65+) with low kidney function who started taking the antidepressant sertraline. Researchers compared the safety of a 50 mg daily dose versus a 25 mg daily dose, tracking hospital visits, emergency department visits, or dea…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Antidepressant dose matters for seniors with kidney trouble
Knowledge-focused CompletedThis study looked at over 12,000 older adults (age 66+) with low kidney function who started taking the antidepressant escitalopram. Researchers compared the safety of a 10 mg daily dose versus a 5 mg daily dose. The goal was to see if the higher dose led to more hospital visits,…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Kidney patients on higher tamsulosin dose face greater danger?
Knowledge-focused CompletedThis study looked at 14,000 older adults (66+) with advanced chronic kidney disease who started taking tamsulosin. Researchers compared those on a higher dose (0.8 mg/day) to those on a lower dose (0.4 mg/day) to see if the higher dose led to more hospital visits or deaths within…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Virtual doctor aims to boost kidney transplant awareness
Knowledge-focused CompletedThis study tested a computer program that acts like a virtual doctor to teach people with advanced chronic kidney disease about kidney transplants. 148 patients took part. The goal was to see if talking with this virtual agent could increase their interest in considering a transp…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Doctors' views on hidden inflammation in heart and kidney patients surveyed
Knowledge-focused CompletedThis study surveyed 1,500 Chinese heart and kidney specialists to understand their awareness and perceptions of systemic inflammation in patients with both atherosclerotic cardiovascular disease and chronic kidney disease. The goal was to learn how doctors currently identify and …
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Real-World study tracks kidney drug use across eastern europe
Knowledge-focused CompletedThis study looked at how doctors in seven Central Eastern European countries prescribe dapagliflozin for chronic kidney disease in routine care. Researchers reviewed medical records of about 1,090 adults to understand who gets the drug and what happens over the next year. The goa…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Higher lorazepam doses may be riskier for seniors with weak kidneys
Knowledge-focused CompletedThis completed study looked at over 12,000 older adults (66+) with low kidney function who started taking lorazepam. Researchers compared higher doses (1-4 mg/day) to lower doses (0.5-1 mg/day) to see if there was a greater risk of hospitalization, emergency visits, or death with…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC