CHRONIC KIDNEY DISEASE(CKD)
Clinical trials for CHRONIC KIDNEY DISEASE(CKD) explained in plain language.
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New device aims to improve dialysis access for kidney patients
Disease control CompletedThis study tested a new device called FLEX-1 to create a special blood vessel connection (arteriovenous fistula) for people with advanced chronic kidney disease who need dialysis. The study included 17 adults with stage 4 or 5 kidney disease. The goal was to see if the device was…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated May 17, 2026 07:04 UTC
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New hope for dialysis patients: drug AP301 targets dangerous phosphorus levels
Disease control CompletedThis study tested a new drug called AP301 in 474 adults with end-stage kidney disease on dialysis who have high phosphorus levels. The goal was to see if AP301 can safely lower phosphorus better than the current standard treatment, sevelamer carbonate. Participants received eithe…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: PHASE3 • Sponsor: Alebund Pharmaceuticals • Aim: Disease control
Last updated May 17, 2026 06:51 UTC
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New device aims to simplify dialysis access for kidney patients
Disease control CompletedThis study tested a new device called FLEX-1 that creates a special blood vessel connection (arteriovenous fistula) for people with advanced kidney disease who need dialysis. Sixteen adults with stage 4 or 5 chronic kidney disease took part. The goal was to see if the device is s…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated May 17, 2026 06:47 UTC
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Breathing workouts boost lung power in young kidney transplant patients
Disease control CompletedThis study looked at whether special breathing exercises could improve lung function and muscle strength in children who had a kidney transplant. Thirty children aged 8 to 18 who were at least 6 months post-transplant took part. The researchers measured changes in breathing tests…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: Atlas University • Aim: Disease control
Last updated May 01, 2026 15:58 UTC
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Higher antidepressant dose may be risky for seniors with kidney disease
Knowledge-focused CompletedThis study looked at over 12,000 older adults (65+) with low kidney function to see if starting a higher dose (10 mg/day) of the antidepressant escitalopram is riskier than a lower dose (5 mg/day). The goal was to compare rates of hospitalization, emergency visits, or death withi…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 17, 2026 06:48 UTC
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Real-World study reveals how kidney patients use common drug
Knowledge-focused CompletedThis study looked at how doctors in Central Eastern Europe prescribe dapagliflozin for chronic kidney disease (CKD) in routine care. Researchers collected data from medical records of over 1,000 adults to understand who gets the drug and what happens to their health over a year. …
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 17, 2026 06:48 UTC
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Study reveals hidden danger of common anxiety drug in seniors with kidney disease
Knowledge-focused CompletedThis study looked at over 12,000 older adults (age 66+) with low kidney function who started taking lorazepam, a common anxiety medication. Researchers compared those taking higher doses (more than 1 mg per day) to those on lower doses (0.5-1 mg per day) to see if they had a high…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 17, 2026 06:48 UTC
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Higher dose of common prostate drug may pose risks for seniors with kidney disease
Knowledge-focused CompletedThis study reviewed health records of 14,000 older adults (66+) with advanced chronic kidney disease who started taking tamsulosin, a drug for prostate issues. Researchers compared those on a higher dose (0.8 mg/day) to those on a lower dose (0.4 mg/day) to see if the higher dose…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Higher antidepressant dose may pose risks for seniors with weak kidneys
Knowledge-focused CompletedThis study looked at over 7,000 older adults (65+) with reduced kidney function to see if starting a higher dose (20 mg/day) of the antidepressant citalopram is riskier than a lower dose (10 mg/day). Researchers checked for hospital visits, emergency department visits, or death w…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Virtual agent aims to boost kidney transplant awareness
Knowledge-focused CompletedThis study tested a computer-based virtual healthcare agent that talks with patients who have advanced chronic kidney disease. The goal was to see if the agent could help patients and their caregivers learn more about kidney transplantation and feel more ready to discuss it. 148 …
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Simple medication check slashes hospital return for kidney patients?
Knowledge-focused CompletedThis study looked at whether a thorough review of medications at hospital discharge could reduce mistakes and prevent patients with chronic kidney disease from being readmitted within 90 days. Researchers compared 323 adults who received this extra medication check to a similar g…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Doctors polled on hidden inflammation link in heart and kidney patients
Knowledge-focused CompletedThis study surveyed 1,500 heart and kidney specialists in China to understand how they think about inflammation in patients with both heart disease and chronic kidney disease. The goal was to learn what doctors know and do about inflammation in these patients. No treatments or te…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Kidney patients: higher pramipexole dose may raise hospital risk
Knowledge-focused CompletedThis completed study looked at 1,100 older adults (65+) with advanced chronic kidney disease who started taking pramipexole, a drug for restless legs or Parkinson's. Researchers compared higher starting doses to a very low dose to see if there was a greater risk of hospitalizatio…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC
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Sleep aid trazodone may pose hidden danger for seniors with weak kidneys
Knowledge-focused CompletedThis study examined over 31,000 older adults (65+) with chronic kidney disease to see if starting a higher dose of the sleep medication trazodone (75-150 mg/day) increases the risk of hospitalization, emergency visits, or death within 30 days compared to a lower dose (25-75 mg/da…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC
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Antidepressant dose safety checked in seniors with kidney disease
Knowledge-focused CompletedThis study reviewed health records of nearly 7,000 older adults (age 66+) with low kidney function to see if starting a higher dose (50 mg/day) of the antidepressant sertraline was riskier than a lower dose (25 mg/day). The researchers looked at whether people had to go to the ho…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC