CHRONIC KIDNEY DISEASE(CKD)
Clinical trials for CHRONIC KIDNEY DISEASE(CKD) explained in plain language.
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New drug aims to tame dangerous mineral in kidney patients
Disease control CompletedThis study tested a new drug called AP301 to see if it works as well as or better than a standard medication (sevelamer) at controlling high phosphorus levels in the blood of people on long-term dialysis. It involved 474 Chinese adults with chronic kidney disease who were receivi…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: PHASE3 • Sponsor: Alebund Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New device aims to make kidney dialysis safer and more reliable
Disease control CompletedThis study tested a medical device called FLEX-1 that helps create better connections for dialysis treatment in patients with advanced kidney disease. Researchers wanted to see if this device was safe and effective for creating the blood vessel access needed for regular dialysis …
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Simple medication check could keep kidney patients out of the hospital
Disease control CompletedThis study tested whether a careful review of a patient's medications when they leave the hospital helps people with chronic kidney disease. Researchers compared a group that received this extra medication check to a group that got standard hospital care. The main goal was to see…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New device aims to make dialysis easier for kidney patients
Disease control CompletedThis small study tested a medical device designed to create a better connection for dialysis treatment in patients with advanced kidney disease. Researchers wanted to see if the device was safe and effective at creating what's called an arteriovenous fistula, which is a surgical …
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Mar 12, 2026 13:51 UTC
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Can simple breathing exercises help kids breathe easier after a transplant?
Symptom relief CompletedThis study tested whether a special breathing exercise program could help children who have had a kidney transplant. The goal was to see if strengthening their breathing muscles could improve their lung function, overall muscle strength, and ability to walk. Thirty children were …
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: Atlas University • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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Higher antidepressant dose may pose greater risk for seniors with kidney issues
Knowledge-focused CompletedThis study looked at whether starting older adults with reduced kidney function on a higher dose (50mg) of the antidepressant sertraline is riskier than starting on a lower dose (25mg). Researchers analyzed health records from over 6,800 adults aged 66+ in Canada who were newly p…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Apr 02, 2026 00:41 UTC
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Higher antidepressant dose may put elderly kidney patients at risk
Knowledge-focused CompletedThis study looked at the safety of two different starting doses of the antidepressant citalopram in adults aged 66 and older who have reduced kidney function. Researchers analyzed health records of over 7,000 people to see if starting on a 20mg daily dose led to more hospital vis…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Doctors polled on hidden inflammation link between heart and kidney disease
Knowledge-focused CompletedThis study surveyed 1500 heart and kidney doctors in China. The goal was to understand their awareness and views on the role of body-wide inflammation in patients who have both heart and kidney disease. The survey asked about how doctors identify and manage this inflammation in t…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Virtual coach aims to bridge kidney transplant knowledge gap
Knowledge-focused CompletedThis study tested a conversational virtual healthcare agent designed to educate patients with advanced chronic kidney disease and their caregivers about kidney transplantation. The tool provided information from the National Kidney Foundation and was tailored to address the speci…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Common prostate Drug's hidden risk for kidney patients revealed
Knowledge-focused CompletedThis study looked at whether a higher dose of the prostate medication tamsulosin is riskier than a lower dose for older adults with advanced kidney disease. Researchers analyzed health records of 14,000 men in Ontario, Canada, comparing those who started on a high dose versus a s…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Higher anxiety drug dose linked to more hospital trips for seniors with kidney issues
Knowledge-focused CompletedThis study looked at whether starting a higher dose of the anxiety/sleep medication lorazepam is riskier than a lower dose for older adults with poor kidney function. Researchers analyzed health records of over 12,000 people aged 66+ in Canada. They compared the chance of being h…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Higher antidepressant dose may pose risk for elderly with kidney issues
Knowledge-focused CompletedThis study looked at the safety of two different starting doses of a common antidepressant, escitalopram, in adults over 65 with reduced kidney function. Researchers analyzed health records of over 12,000 people to see if starting on a 10 mg daily dose led to more hospital visits…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Common Parkinson's drug under scrutiny for kidney patients
Knowledge-focused CompletedThis study looked at whether starting a higher dose of the medication pramipexole is riskier than a lower dose for older adults with advanced kidney disease. Researchers analyzed health records of over 1,100 people in Canada to see if the higher dose was linked to more hospital v…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Higher sleep drug dose may pose risk for seniors with kidney issues
Knowledge-focused CompletedThis study looked at whether starting a higher dose of the sleep and depression medication trazodone is riskier than a lower dose for older adults with reduced kidney function. Researchers analyzed health records of over 31,000 people aged 66 and older in Ontario. They compared t…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Doctors track Real-Life results of kidney drug in eastern europe
Knowledge-focused CompletedThis study observed how doctors use the medication dapagliflozin to treat chronic kidney disease in everyday practice. It followed over 1,000 patients across seven Eastern European countries for up to a year after they started the drug. The goal was to understand which patients r…
Matched conditions: CHRONIC KIDNEY DISEASE(CKD)
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:24 UTC