CESAREAN DELIVERY

This phase 3 trial is testing whether adding a single dose of azithromycin to standard antibiotics can prevent infections in 8,000 women having scheduled C-sections. Participants receive either azithromycin or a placebo, plus usual care. The study tracks infections like wound inf…

This study tests a new method called U-CaVIT, which uses a balloon placed in the uterus to prevent severe bleeding after a C-section in women at high risk. About 70 participants will either get standard care or standard care plus the balloon. The goal is to see if the balloon red…

This study compares two ultrasound-guided pain relief injections—TAP block and ESP block—for women having a planned cesarean section. Both use the same local anesthetic (ropivacaine) to numb nerves, but they target different areas. The main goal is to see which provides better pa…

This study looks at different ways to close the skin after a C-section to find which method leads to the best-looking scar and fewer wound problems. About 52 women having scheduled C-sections will take part. Researchers will take photos of scars and have doctors rate them, and al…

This study tests whether a special numbing shot (TAP block) given during a complex C-section can reduce the need for strong painkillers afterward. About 120 women with a history of multiple abdominal surgeries will participate. The goal is to improve pain control and lower opioid…

This study compares two schedules for taking non-opioid pain relievers (acetaminophen and NSAIDs) after a cesarean delivery: taking them at different times (staggered) or at the same time (simultaneous). The goal is to see which approach better controls pain and reduces the need …

This study is a large registry that collects information from hospitals across the U.S. on pregnant women who receive general anesthesia during a cesarean delivery. Researchers aim to understand why general anesthesia is used, how it is managed, and what outcomes occur for both m…

This study is testing whether inducing labor at 39 weeks in low-risk pregnant women reduces the need for C-sections compared to waiting for labor to start naturally or inducing at 41 weeks. Over 1,000 women in China are taking part. The researchers will also analyze cord blood to…

This study looks at how weight gain during pregnancy affects spinal anesthesia in planned C-sections. Researchers will watch 200 pregnant women and record how the anesthesia works and how their bodies respond. No extra treatments or procedures are given—only routine care. The goa…

This study checks if blood pressure readings from an ankle cuff are as accurate as those from a standard arm cuff during planned C-sections. About 110 women will have their blood pressure measured at both sites. If ankle readings are reliable, mothers could hold their newborns sk…

This study looks at 200 healthy women having a planned C-section under spinal anesthesia. It compares two drugs, norepinephrine and ephedrine, to see which one better keeps the heart pumping blood effectively. Researchers use ultrasound to measure heart function at key times duri…