BRONCHIOLITIS

This study tested whether using HEPA air filters at home can reduce respiratory symptoms in infants under 12 months who were hospitalized for bronchiolitis. 230 babies were randomly assigned to have either real HEPA filters or placebo filters in their home for 24 weeks. Caregiver…

This trial investigates whether inhaling a 50/50 mix of nitrous oxide (laughing gas) and oxygen can reduce pain when a nasogastric tube is placed in children aged 3 months to 3 years. The study includes children with mild to moderate dehydration from conditions like gastroenterit…

This study looked at 300 infants under 6 months old with severe bronchiolitis in the pediatric ICU. Researchers compared two flow rates of high-flow nasal cannula (2 vs 3 liters per minute per kilogram) to see which one reduced breathing failure within 24 hours. The goal is to fi…

This study tested a new ventilator mode called NAVA for people with chronic obstructive pulmonary disease (COPD) who need a breathing machine. NAVA uses the patient's own diaphragm signals to control the machine, aiming to improve comfort and reduce time on the ventilator. The st…

This study looked at 80 children aged 1 month to 5 years with severe breathing problems from pneumonia or bronchiolitis. It compared two non-invasive breathing support methods: High Velocity Nasal Insufflation (HVNI) and Nasal Continuous Positive Airway Pressure (CPAP). The goal …

This study measured the peak tidal inspiratory flow (PTIF)—how fast infants breathe in—in 50 babies under 6 months old with moderate to severe viral bronchiolitis. Researchers used a spirometer to record 20 breaths per infant within 24 hours of hospital admission. The goal was to…

This study looked at 46 infants under 2 years old in the pediatric ICU with severe bronchiolitis. Researchers used a heart ultrasound measure called TAPSE to see if it could predict how long babies needed intensive care. The goal was to find a simple test that helps doctors plan …

This study looked at whether a set of care guidelines (called a pathway) could help doctors and nurses in community hospitals use the best treatments for children hospitalized with asthma, pneumonia, or bronchiolitis. Over 11,000 children took part across many hospitals. The goal…

This completed study analyzed how doctors in different hospitals treat babies under 2 years old with bronchiolitis, a common lung infection. Researchers looked at 127 children to see if differences in care led to different outcomes, like length of hospital stay. The goal was to u…

This study followed 29 infants who had bronchiolitis in their first year to see if their lung function changes over time and whether that leads to asthma. Researchers measured breathing using special tests and also did allergy skin tests. However, many families dropped out, so th…

This study observed over 1,800 children hospitalized for serious breathing problems like bronchiolitis, pneumonia, or asthma. It aimed to track how many children were hospitalized for bronchiolitis after a new immunization became available. The study did not test any new treatmen…

This study tested a nurse-led weaning protocol for high-flow nasal cannula (HFNC) oxygen therapy in 150 infants aged 1-24 months hospitalized with bronchiolitis. The goal was to see if a structured weaning plan could reduce the time on HFNC, shorten hospital stays, and lower cost…