New ventilator mode may cut breathing tube time for lung disease patients
NCT ID NCT05595733
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested a new ventilator mode called NAVA for people with chronic obstructive pulmonary disease (COPD) who need a breathing machine. NAVA uses the patient's own diaphragm signals to control the machine, aiming to improve comfort and reduce time on the ventilator. The study enrolled 50 adults and compared how many days they were alive and off the ventilator versus standard care.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Obstructive pulmonary diseases include chronic obstructive pulmonary disease (COPD), asthma (Asthma), cystic fibrosis (cystic fibrosis), bronchiectasis (bronchiectasis), bronchiolitis or other diseases that cause airway stenosis, etc. 2. Other patients with obstructive pulmonary disease assessed by the clinical team 3. Consent signed by the principal or legal representative 4. Age \> 20 years old and \< 99 years old Exclusion Criteria: 1. Those who cannot place a nasogastric tube due to medical conditions 2. Pregnant women 3. Those who have received gas cutting 4. Patients with phrenic nerve palsy 5. Neuromuscular disease 6. Intubation due to cardiac arrest
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fu Jen Catholic University Hospital All Rights Reserved
Taipei, 24352, Taiwan
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