Which flow rate helps babies breathe better? new study tests two options

NCT ID NCT02824744

Completed Symptom relief Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 300 infants under 6 months old with severe bronchiolitis in the pediatric ICU. Researchers compared two flow rates of high-flow nasal cannula (2 vs 3 liters per minute per kilogram) to see which one reduced breathing failure within 24 hours. The goal is to find the safest and most effective way to support breathing in these babies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high-flow nasal cannula (HFNC) device
What this could lead to: If successful, this study could identify the best flow rate to help infants with severe bronchiolitis breathe easier and avoid needing a breathing tube.
What could go wrong: This is a completed trial comparing two similar treatments, so the difference in benefit may be small. Results may not apply to all infants or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bronchiolitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIOLITIS

Contacts and locations

Locations

University hospital of Montpellier

Montpellier, 34285, France

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