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Could a lower oxygen threshold get kids home sooner?

NCT ID NCT06016244

Completed Disease control Sponsor: Spaarne Gasthuis Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether using a lower oxygen saturation threshold (88%) versus the standard (92%) to decide when to give supplemental oxygen helps children aged 6 weeks to 12 years recover faster from respiratory distress. Participants are randomly assigned to one of two groups, and researchers measure how long it takes to meet discharge criteria. The goal is to find a safe, cost-effective approach that shortens hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxygen saturation threshold (88% or 92%) for deciding when to give supplemental oxygen
What this could lead to
If successful, this could establish a safe, cost-effective oxygen target that shortens hospital stays and speeds recovery for children with breathing problems.
What could go wrong
This is a single-center trial, and results may not apply to all hospitals or children. The lower threshold (88%) might not be safe for every child, and the study may not detect rare complications.

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Conditions

The condition(s) this trial relates to.

Bronchial Hyperreactivity bronchiolitis lower respiratory tract disorder reactive airway disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIAL HYPERREACTIVITY BRONCHIOLITIS LOWER RESPIRATORY TRACT INFECTION

Contacts and locations

Locations

  • Amphia Ziekenhuis

    Breda, Netherlands

  • Canisius Wilhelmina Ziekenhuis

    Arnhem, Netherlands

  • Franciscus Gasthuis en Vlietland

    Rotterdam, Netherlands

  • Isala Klinieken

    Zwolle, Netherlands

  • Martini Ziekenhuis

    Groningen, Netherlands

  • Rijnstate Ziekenhuis

    Arnhem, Netherlands

  • Spaarne Gasthuis

    Haarlem, North Holland, 2035 RC, Netherlands

  • St Antonius Ziekenhuis

    Nieuwegein, Netherlands

  • Tergooi Ziekenhuis

    Hilversum, Netherlands

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