Air purifiers tested to soothe baby lungs after bronchiolitis

NCT ID NCT05615870

Completed Disease control Sponsor: IDeA States Pediatric Clinical Trials Network Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using HEPA air filters at home can reduce respiratory symptoms in infants under 12 months who were hospitalized for bronchiolitis. 230 babies were randomly assigned to have either real HEPA filters or placebo filters in their home for 24 weeks. Caregivers tracked days without coughing, wheezing, or trouble breathing. The goal is to see if cleaner indoor air helps babies recover faster and avoid more doctor visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: HEPA filtration unit
What this could lead to: If effective, using HEPA filters at home could reduce coughing, wheezing, and breathing trouble in infants after bronchiolitis.
What could go wrong: This is a completed trial, but results are not yet published. The benefit may be small or not apply to all infants.

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Conditions

The condition(s) this trial relates to.

bronchiolitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIOLITIS

Contacts and locations

Locations

Alaska Native Tribal Health Consortium

Anchorage, Alaska, 99508, United States
Arkansas Children's Hospital - Little Rock (ACHRI)

Little Rock, Arkansas, 72202, United States
Avera Research Institute

Sioux Falls, South Dakota, 57108, United States
Children's Hospital OU Medical Center

Oklahoma City, Oklahoma, 73104, United States
Dartmouth Hospital

Lebanon, New Hampshire, 03756, United States
Kansas University Medical Center

Kansas City, Kansas, 66160, United States
Kapi'olani Medical Center for Women and Children

Honolulu, Hawaii, 96826, United States
Prisma Health-Midlands

Columbia, South Carolina, 29203, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Tulane University, Department of Pediatrics

New Orleans, Louisiana, 70112, United States
University of Louisville

Louisville, Kentucky, 40292, United States
University of Miss. Medical Center

Jackson, Mississippi, 39216, United States
University of Montana

Missoula, Montana, 59812, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Health Sciences Center

Albuquerque, New Mexico, 87131, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
West Virginia University

Morgantown, West Virginia, 26506, United States

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