BRAIN TUMOR

This early-stage study tested a new oral medication called CUDC-907 in children and young adults whose cancers had returned or stopped responding to standard treatments. The main goals were to check for side effects and find the safest dose for children, since this drug had only …

This early-stage study tested whether combining two existing cancer drugs (pembrolizumab and vorinostat) with standard chemotherapy and radiation is safe for people newly diagnosed with glioblastoma, an aggressive brain tumor. The trial involved 21 participants to determine the h…

This study tested whether a drug called dexmedetomidine, given during anesthesia, could help protect the brain during surgery to remove a tumor. Researchers wanted to see if it could reduce brain stress and inflammation, potentially leading to better recovery and thinking skills …

This study tested a new MRI contrast agent called RVP-001, which uses manganese instead of gadolinium, to see if it could safely and effectively detect lesions in the brain and central nervous system. It involved 18 adults with known conditions like brain tumors or multiple scler…

This study tested a new, highly sensitive ultrasound method to create maps of active brain areas during surgery for brain tumors or lesions. The goal was to see if this new, real-time method could work as well as the current gold-standard mapping techniques used by surgeons. It i…

This study looked at whether a special type of PET scan (FDOPA-PET) can better tell the difference between brain tumors and non-cancerous brain lesions. Researchers analyzed past scan data from 74 patients who had suspicious brain findings on an MRI. The goal was to find the best…

This small, early-stage study tested a new type of combined PET and MRI scan to see if it could take clearer pictures of brain tumors. It involved 5 adult patients with new or suspected returning brain tumors who were already scheduled for treatment. The goal was to gather initia…

This study tested whether watching 360° virtual reality movies could help reduce fear and anxiety in cancer patients about to begin radiation therapy. Researchers enrolled 292 adults with breast, lung, prostate, head and neck cancers, or brain tumors. Patients watched VR movies s…

This study tested a special therapy program designed to help people with advanced brain cancer manage the emotional distress that comes with their diagnosis. Researchers compared the therapy, called CALM, to standard care in 60 patients. The main goal was to see if the program wa…

This study tested whether a 12-week home exercise program could help improve memory and attention in children who had radiation therapy for a brain tumor. Researchers enrolled 36 children, ages 8 to 17, who were at least one year past treatment and had reported thinking or memory…

This small pilot study tested whether a new telehealth program called C-SMART is practical and acceptable for brain tumor patients experiencing mild thinking and memory problems. The main goal was to see if patients and their caregivers could be recruited and complete the program…

This study tested whether a short online training course could improve the ability of emergency department doctors and nurses to accurately read CT scans of the head. The goal was to see if this training could help them identify critical problems like strokes or brain bleeds more…

This study aimed to better understand brain and spinal cord tumors by observing over 1,200 adult patients over time. Researchers collected medical information, scans, and tissue samples to learn how these cancers progress and to identify areas for future treatment research. The s…

This study followed children and young adults who had proton radiation for brain or spinal cord tumors. Researchers wanted to see how their thinking skills, emotions, and behavior changed over time, and whether they needed special help in school. They collected this information b…