New ultrasound technique could help surgeons see brain activity in real time

NCT ID NCT02656407

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a new, highly sensitive ultrasound technique to map brain activity during surgery in 23 adults with brain tumors or lesions. The method aims to provide real-time images of blood flow changes linked to brain function, without needing contrast agents. Researchers compared it to standard methods like cortical stimulation mapping and functional MRI to see if it could accurately identify active brain areas.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ultrasound device (Aixplorer)
What this could lead to: If successful, this could provide a cheaper, real-time way to map brain function during surgery, potentially improving surgical precision.
What could go wrong: This is a small, early-stage study (23 people) testing a new imaging method. It may not prove better than existing techniques, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN LESION BRAIN TUMOR

Contacts and locations

Locations

Pitié Salpetriere Hospital

Paris, Île-de-France Region, 75013, France

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