BIPOLAR II DISORDER

This study tested an experimental drug called ABBV-932 in 161 adults with bipolar I or II disorder who were currently experiencing a depressive episode. Participants took either the drug or a placebo daily for 6 weeks to see if it safely improves mood and reduces depression sympt…

This study looked at whether repeated low-dose ketamine infusions could help people with treatment-resistant bipolar depression keep feeling better over 12 weeks. Forty-one adults who had already responded to an initial course of ketamine received up to six more infusions on a fl…

This study tested an investigational medication called BXCL501 for calming agitation episodes in people with bipolar disorder, schizophrenia, or related conditions. 452 adults took either the drug or a placebo, and researchers measured changes in agitation levels and safety. The …

This study tested four doses of intravenous ketamine in 71 adults with treatment-resistant bipolar depression. Participants received either ketamine or a sedative (midazolam) over two weeks. The goal was to see if ketamine could safely reduce depression symptoms. Results focused …

This study looked at whether family members or caregivers can help measure agitation in people with bipolar disorder or schizophrenia. 33 adults took a single dose of an experimental medicine, and researchers compared ratings from doctors, patients, and their family members. The …