New agitation drug igalmi tested for repeated use in mental health conditions

This completed study tested Igalmi, a fast-dissolving film placed under the tongue, for managing frequent agitation in people with schizophrenia or bipolar disorder. 29 adults received the drug as needed for 7 days in a clinic. Researchers looked for signs that the drug might stop working over time (tolerance) or cause withdrawal symptoms when stopped. The goal was to understand how safe and effective repeated use is for calming agitation.