Ketamine boost keeps bipolar depression at bay in small trial

NCT ID NCT05339074

First seen Sep 30, 2025 · Last updated Jun 18, 2026 · Updated 42 times

Summary

This study looked at whether repeated ketamine infusions can help people with hard-to-treat bipolar depression stay well. 41 adults who had already responded to an initial course of ketamine received up to 6 more infusions over 12 weeks. The goal was to see if maintenance doses could keep depressive symptoms low and improve quality of life.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BIPOLAR DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Ontario Shores Centre for Mental Health Sciences

    Whitby, Ontario, L1N 5S9, Canada

  • Toronto General Hospital

    Toronto, Ontario, M5G 2C4, Canada

  • Toronto Western Hospital

    Toronto, Ontario, M5T 2S8, Canada

Conditions

The condition(s) this trial relates to.

bipolar depression bipolar disorder bipolar I disorder bipolar II disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.