BILIARY ATRESIA

This study looks at whether a special diet high in medium-chain triglycerides (MCTs) can help infants with biliary atresia grow better after Kasai surgery. About 300 infants under 3 months old who had the surgery will be followed. Researchers will track weight and length to see i…

This study looks at whether a special high-MCT formula given before and after Kasai surgery can help infants with biliary atresia grow better. About 120 infants under 3 months old will take part. The formula is designed to be easier for the damaged liver to process and may improv…

This study tests whether a safe fluorescent dye, called indocyanine green (ICG), can help diagnose biliary atresia in infants under 3 months old. The dye is injected and normally appears in the stool if the bile ducts are open. If no glow is seen in the stool, it may indicate a b…

This study tests a new way to diagnose biliary atresia, a serious liver condition in newborns where bile ducts are blocked. Infants with jaundice will receive a safe dye (ICG) through an IV, and their diapers will be checked for a glow that shows bile is flowing. The goal is to s…

This study tests whether giving daily oral antibiotics to infants with biliary atresia after Kasai surgery can prevent cholangitis, a serious liver infection. About 356 babies will be randomly assigned to receive antibiotics or not, and their health will be tracked for two years.…

This study is gathering information and samples from over 1,200 children with biliary atresia, a rare liver disease. Researchers hope to find the genes that cause the disease and learn how it progresses over time in children who still have their own liver. No new treatments are b…

This study looks at whether a substance called FGF19 in the blood, measured before surgery, can help predict how well children with biliary atresia will recover. Researchers will follow 200 children for one year after surgery to see if FGF19 levels are linked to liver health and …

This study is building a large database of medical information and biological samples from up to 1,000 infants with cholestasis (a condition that causes jaundice). The goal is to track how the disease changes over time and to support future research into better treatments for liv…

This study aims to uncover the genetic causes of biliary atresia, a rare liver disease in newborns that often leads to liver failure and transplant. Researchers will analyze DNA from 1,100 children who have had or need a liver transplant. By finding the genes involved, they hope …