Massive study aims to unlock genetic secrets of rare liver disease in kids
NCT ID NCT00345553
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is collecting medical information, genetic material, and body fluid samples from over 1,200 children with biliary atresia, a rare liver disease. The goal is to find genes that cause the disease and understand how it progresses in children who still have their own liver. No new treatments are being tested; instead, researchers hope to learn more about the disease to guide future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify genes linked to biliary atresia and better predict how the disease progresses in children who haven't had a liver transplant.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve health. It may take years to yield useful insights, and genetic findings may not apply to all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BILIARY ATRESIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60614, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Children's Healthcare of Atlanta - Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact
Contact
-
Children's Hospital Colorado
RECRUITINGAurora, Colorado, 80045, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
-
Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Children's Hospital of Los Angeles
RECRUITINGLos Angeles, California, 90027, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Hospital for Sick Children
COMPLETEDToronto, Ontario, M5G 1X8, Canada
-
Johns Hopkins School of Medicine
COMPLETEDBaltimore, Maryland, 21287, United States
-
Mount Sinai Medical Center
COMPLETEDNew York, New York, 10029, United States
-
Riley Children's Hospital
COMPLETEDIndianapolis, Indiana, 46202, United States
-
Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Texas Children's Hospital (Baylor College of Medicine)
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
UPMC Children's Hospital of Pittsburgh
COMPLETEDPittsburgh, Pennsylvania, 15224, United States
-
University of California at San Francisco
COMPLETEDSan Francisco, California, 94143, United States
-
University of Utah
RECRUITINGSalt Lake City, Utah, 84113, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Washington University School of Medicine
COMPLETEDSt Louis, Missouri, 63110, United States