What drives a rare liver disease in newborns? a genetic deep dive aims to find out

NCT ID NCT04272515

Recruiting now Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

Biliary atresia is a rare but serious liver condition in newborns that often leads to transplantation. This study collects blood, skin, and liver tissue samples from affected children to search for the genes and cellular pathways that cause the disease. By understanding the molecular roots, researchers hope to lay the groundwork for better diagnosis or treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If key genes or pathways are found, this could point toward future treatments or earlier diagnosis for biliary atresia.
What could go wrong: This is an observational sample-collection study, not a treatment trial. It may not identify clear causes, and any discoveries would need years of further research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

biliary atresia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BILIARY ATRESIA

Contacts and locations

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Locations

Hopital Necker enfants malades
RECRUITING

Paris, De, 75015, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
PRC Inserm
NOT_YET_RECRUITING

Paris, 75013, France

Contact Phone: •••-•••-•••• Email: •••••@•••••

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