Glowing poop test could spot rare infant liver disease
NCT ID NCT07513038
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a fluorescent dye called indocyanine green (ICG) can help diagnose biliary atresia, a rare liver disease in infants where bile ducts are blocked. After injection, the dye is normally removed through bile and appears in stool. In infants with biliary atresia, the dye should not appear in stool. Researchers will check stool samples with a special camera to see if the dye is present. The study involves 20 infants under 3 months old who are already being evaluated for the condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Indocyanine Green (ICG)
What this could lead to
If successful, this could provide a simpler, non-invasive way to diagnose biliary atresia in infants, potentially replacing more complex tests.
What could go wrong
This is an early-phase study with only 20 infants. The test may not reliably distinguish biliary atresia from other causes of jaundice, and results may not apply to all infants.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••