AVASCULAR NECROSIS
Clinical trials for AVASCULAR NECROSIS explained in plain language.
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New modular shoulder implant aims to improve outcomes in tough revision surgeries
Disease control OngoingThis study is testing a new modular shoulder replacement system in 105 people who need complex revision surgery due to joint disease, trauma, or cancer. The device can replace part or all of the upper arm bone. Researchers are tracking how long the implant lasts and how well pati…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New hip stem implant tracked for 10 years in 313 patients
Disease control OngoingThis study looks at how well the Insignia Hip Stem works and how safe it is for people needing a total hip replacement. It includes 313 adults with conditions like hip arthritis or fractures. Researchers will check implant survival and hip function for up to 10 years after surger…
Matched conditions: AVASCULAR NECROSIS
Phase: NA • Sponsor: Stryker Orthopaedics • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New shoulder implant tracked in 200 patients for pain and function
Disease control OngoingThis study follows 200 adults getting a shoulder replacement with the Zimmer Trabecular Metal Reverse Shoulder System. It aims to see how long the implant lasts and how well it relieves pain and improves movement in people with conditions like arthritis, fractures, or failed prio…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Could a common muscle drug and vitamin e heal jaw bone death?
Disease control OngoingThis phase 3 trial tests whether a combination of pentoxifylline (a muscle pain drug) and vitamin E can help heal jaw bone damage caused by osteoporosis or cancer treatments. About 100 people with medication-related jaw bone death will receive either the drug combo plus standard …
Matched conditions: AVASCULAR NECROSIS
Phase: PHASE3 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New study tests whether No-Cement knee implants outperform traditional ones
Disease control OngoingThis study compares two types of total knee replacement systems: one that uses cement to hold the implant in place and one that does not. Researchers will track 300 patients with knee pain from arthritis or deformity over 5 years to see which implant leads to better pain relief, …
Matched conditions: AVASCULAR NECROSIS
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New hip implant under study for Long-Term success
Disease control OngoingThis study is checking how well a new hip replacement part (the HYPE stem) works and lasts over 10 years. About 180 people with hip disease from arthritis or injury will get the implant. Doctors will use X-rays and surveys to see if the implant stays firmly in place and helps red…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Societe dEtude, de Recherche et de Fabrication • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Shoulder device under 10-Year watch
Disease control OngoingThis study follows 194 people who received the Comprehensive Nano shoulder device to replace their shoulder joint due to arthritis, bone death, or deformity. Researchers will track how long the implant lasts and how well patients can use their shoulder over 10 years. The goal is …
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New knee device tracked in 757-Patient study
Disease control OngoingThis study follows 757 people who received the Persona Partial Knee system, a device used to replace only the damaged part of the knee. The goal is to see how long the implant lasts and how well patients function afterward. Participants have knee arthritis or related conditions a…
Matched conditions: AVASCULAR NECROSIS
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New combo treatment aims to save hips from collapse
Disease control OngoingThis study tests a procedure for people with early-stage osteonecrosis (bone death) of the hip. Doctors drill into the hip bone, inject a concentrated sample of the patient's own bone marrow, and add a special bone graft material called Genex. The goal is to see if this helps bon…
Matched conditions: AVASCULAR NECROSIS
Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New shoulder replacement system tracked in global study
Disease control ENROLLING_BY_INVITATIONThis study is following 110 people who received a Tornier HRS shoulder replacement to see how well it improves pain and function. Participants have conditions like arthritis, fractures, or rotator cuff tears. The goal is to collect long-term safety and performance data for regula…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Stryker Trauma and Extremities • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New shoulder implant tracked for 10 years in 73 patients
Disease control OngoingThis study follows 73 people who received a shoulder replacement using the Anatomical Shoulder Domelock System. The goal is to see how well the device works and how safe it is over 10 years. Participants have conditions like arthritis or avascular necrosis and have not improved w…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Hip implants under the microscope: 8-Year Follow-Up study launched
Disease control ENROLLING_BY_INVITATIONThis study is checking the long-term safety and performance of two hip implant devices (RingLoc Bipolar Acetabular Cup and Endo II Femoral Head) used in hip replacement surgery. Researchers will follow 116 patients who had their surgery at least eight years ago, tracking complica…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New hip implant aims to improve joint replacement outcomes
Disease control OngoingThis study is testing the CATALYSTEM hip system in 119 people who need a total hip replacement due to conditions like arthritis or hip damage. The goal is to see if the implant is safe and works well, focusing on how long it lasts without needing a second surgery. Participants wi…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New knee implant under review: will it hold up?
Disease control OngoingThis study follows 100 people who received a new type of knee replacement device called EVOLUTION® NitrX™. The goal is to see how safe and effective it is over time. Participants have conditions like arthritis or knee damage. The main measure is a patient-reported score of knee f…
Matched conditions: AVASCULAR NECROSIS
Sponsor: MicroPort Orthopedics Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New shoulder implant under review: will it hold up over time?
Disease control OngoingThis study looks at how well a special shoulder implant works for people who need a joint replacement due to arthritis, injury, or bone loss. Researchers will track 22 participants to see how long the implant lasts and if there are any problems. The goal is to make sure the impla…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New knee implant under review: could it ease arthritis pain?
Disease control OngoingThis study is testing the Persona Ti-Nidium knee implant in 240 people who need total knee replacement due to conditions like osteoarthritis or rheumatoid arthritis. The goal is to see if the implant is safe and improves knee function and pain. Participants will be followed over …
Matched conditions: AVASCULAR NECROSIS
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New hip liner under Long-Term watch: will it hold up?
Disease control ENROLLING_BY_INVITATIONThis study is following 202 people who received a special hip liner during hip replacement surgery. The goal is to see how long the liner lasts and whether it causes any problems over time. Participants are adults aged 18 to 80 with conditions like arthritis or hip fractures. The…
Matched conditions: AVASCULAR NECROSIS
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New shoulder implant tracked in 200 patients for lasting relief
Disease control OngoingThis study follows 200 adults who received the Medacta Shoulder System to treat shoulder problems like arthritis, fractures, or to replace a previous implant. Researchers are checking how long the implant lasts, how well the shoulder works, and any side effects. The goal is to co…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Medacta International SA • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New hip stem under surveillance: how well does it last?
Disease control OngoingThis study follows 100 people who need a hip replacement to see how long the MiniMAX hip stem lasts and how well it works. Participants receive the stem during surgery and are checked for implant survival and hip function using the Harris Hip Score. The goal is to confirm the ste…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Medacta International SA • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New knee implant under watch: will it last?
Disease control OngoingThis study follows 200 people who receive a cementless knee replacement (GMK Sphere) to see how long the implant lasts and how well it works. Participants have severe knee damage from arthritis or other conditions. The goal is to monitor safety and performance in real-world use, …
Matched conditions: AVASCULAR NECROSIS
Sponsor: Medacta International SA • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New hip implant tested for better Long-Term fit
Disease control OngoingThis study compares a new hip implant cup (Trident II) to an older version to see if it stays just as stable in the bone after surgery. Researchers will track 87 patients aged 40-75 for up to 10 years using special X-rays to measure any implant movement. The goal is to ensure the…
Matched conditions: AVASCULAR NECROSIS
Phase: NA • Sponsor: Region Skane • Aim: Disease control
Last updated Jun 26, 2026 14:06 UTC
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Shoulder implant safety tracked for years after surgery
Knowledge-focused OngoingThis study follows 76 people who received a pyrocarbon shoulder implant to see how well it works and holds up over 5 to 10 years. Researchers measure shoulder pain, function, and any complications. The goal is to confirm the implant is safe and effective for long-term use.
Matched conditions: AVASCULAR NECROSIS
Sponsor: Stryker Trauma and Extremities • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Hip implant under observation: will it last?
Knowledge-focused OngoingThis study is following 230 adults who received a G7 hip replacement system to see how long the implant lasts and how well it works. Participants have hip problems like arthritis or bone death. The study does not test a new treatment but simply watches and records outcomes over t…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Researchers track shoulder implant longevity to improve future surgeries
Knowledge-focused OngoingThis study gathers information from 160 people who received a shoulder implant to see how long the implant lasts and how safe it is. Participants have conditions like arthritis or fractures. The goal is to use this data to make better implants and help doctors and patients make i…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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New shoulder implant under watch: how well does it last?
Knowledge-focused OngoingThis study follows 200 adults who received the Medacta Shoulder System to treat various shoulder issues like arthritis, fractures, or rotator cuff problems. The main goal is to see how long the implant lasts and how well the shoulder works after surgery. It is a post-market check…
Matched conditions: AVASCULAR NECROSIS
Sponsor: Medacta International SA • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC