ARTHROPLASTY, REPLACEMENT, KNEE
Clinical trials for ARTHROPLASTY, REPLACEMENT, KNEE explained in plain language.
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New knee system shows promise in 241-Patient trial
Disease control CompletedThis study looked at how well a specific knee replacement system (the DePuy LCS Complete) works in 241 people who needed a new knee joint. The goal was to see if the system performed well during surgery and over time. Results focused on knee function, pain, and how long the impla…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: PHASE4 • Sponsor: DePuy International • Aim: Disease control
Last updated May 17, 2026 03:08 UTC
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New blood clot pill could replace needles for joint replacement patients
Prevention CompletedThis study compared an experimental oral blood thinner (Dimolegin) to standard heparin injections (Clexane) for preventing dangerous blood clots in 215 adults undergoing hip or knee replacement. The goal was to see if the pill works as well as the shot while being easier to take.…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: PHASE3 • Sponsor: Avexima Diol LLC • Aim: Prevention
Last updated May 17, 2026 03:01 UTC
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Veterans' knee surgery recovery boosted by mindset training
Symptom relief CompletedThis study tested whether a brief behavioral therapy called Acceptance and Commitment Therapy (ACT) can help at-risk veterans avoid persistent pain and disability after total knee replacement. 402 veterans scheduled for knee surgery were randomly assigned to receive either ACT or…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated May 17, 2026 03:09 UTC
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Knee replacement pain study: could a simple IV drug replace nerve blocks?
Symptom relief CompletedThis study tested whether giving lidocaine through an IV works as well as a targeted nerve block for controlling pain after knee replacement surgery. 120 adults having a knee replacement took part. The goal was to see if the IV method could reduce the need for strong opioid paink…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: PHASE4 • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated May 17, 2026 02:59 UTC
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Which nerve block eases knee replacement pain better? new study investigates
Symptom relief CompletedThis study looked at 60 adults having knee replacement surgery to compare two types of nerve blocks for pain relief. One group received a BiFeS block plus an adductor canal block, while the other got an IPACK block plus an adductor canal block. Researchers measured pain scores an…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Sponsor: Karabuk University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Ear acupuncture eases pain and swelling after knee replacement
Symptom relief CompletedThis study tested whether ear acupoint therapy (a type of acupuncture on the ear) can help people recover better after total knee replacement surgery. 116 adults aged 50-80 who had knee replacement received ear acupoint therapy along with standard care. The goal was to see if it …
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Sponsor: Peking Union Medical College • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Knee surgery selfies: can photos boost recovery?
Symptom relief CompletedThis study looked at whether showing people pictures of their knee damage and the new joint taken during surgery helps them feel better and move better early after a total knee replacement. About 80 adults with severe knee arthritis took part. The goal was to see if seeing the in…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: NA • Sponsor: Bezmialem Vakif University • Aim: Symptom relief
Last updated May 13, 2026 16:04 UTC
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Study aims to perfect bleeding drug dose for joint replacements
Knowledge-focused CompletedThis study looked at how to best dose tranexamic acid (TXA), a drug that reduces bleeding, during hip or knee replacement surgery. Researchers tested different doses in 21 adults to see how the drug moves through the body. The goal is to create new dosing guidelines, especially f…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: PHASE2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated May 15, 2026 12:07 UTC
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Knee implant showdown: which design helps you walk better?
Knowledge-focused CompletedThis study looked at 20 people with severe knee arthritis who needed a knee replacement. They were split into two groups: one got a rotating platform implant and the other a fixed platform implant. Researchers used 3D motion capture to analyze their walking before and after surge…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: NA • Sponsor: Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Rehab or not? new study challenges physical therapy after joint replacement
Knowledge-focused CompletedThis study looked at whether physical rehabilitation after hip or knee replacement surgery is actually better than no rehabilitation. 169 adults who had a hip or knee replaced due to arthritis took part. The main goal was to see if rehab improves daily activities like walking and…
Matched conditions: ARTHROPLASTY, REPLACEMENT, KNEE
Phase: NA • Sponsor: Troels Mark Christensen • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC