New knee implant tested for better mobility and longevity

NCT ID NCT00733915

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested the DePuy LCS Complete mobile-bearing total knee system in 241 people needing knee replacement due to arthritis. The goal was to see how well the implant and surgical tools work during and after surgery. Researchers measured implant survival, knee function, and patient-reported outcomes like pain and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DePuy LCS Complete mobile-bearing total knee system (a prosthetic knee implant device)

What this could lead to

If successful, this study could confirm that the LCS Complete knee system is a reliable option for knee replacement, potentially improving mobility and reducing pain for people with severe knee arthritis.

What could go wrong

This is a single-group, non-comparative study, so results may not show how it compares to other knee implants. Long-term success depends on factors like patient health and surgical technique, and some patients may still experience complications or need revision surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aagenaes syndrome osteoarthritis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Musgrave Park Hospital

    Belfast, BT9 7JB, Ireland