Study aims to perfect bleeding control drug for joint replacements

NCT ID NCT05075200

First seen Jan 05, 2026 · Last updated Apr 28, 2026 · Updated 19 times

Summary

This study looked at 21 adults having hip or knee replacement to find the best dose of tranexamic acid (TXA), a drug that reduces bleeding and the need for blood transfusions. Participants received either the standard dose or a lower dose if they had kidney problems. Researchers measured TXA levels in the blood to create new dosing guidelines.

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Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, Canada

Conditions

Explore the condition pages connected to this study.