APLASTIC ANEMIA

This study looks at a modified approach to prevent and treat cytomegalovirus (CMV) infection in people who have had a donor stem cell transplant for blood cancers or disorders. About 153 participants are involved, and the goal is to see if changing when and how anti-CMV drugs are…

This early-phase study tests whether adding specially treated immune cells (called veto cells) from a donor can help stem cell transplants work better in people with blood cancers like leukemia or lymphoma. The goal is to help the donor cells grow without causing severe graft-ver…

This study tests a bone marrow transplant method that avoids harsh drugs and radiation, which can worsen lung and liver disease or raise cancer risk in people with dyskeratosis congenita. About 40 participants with bone marrow failure will receive this gentler approach. The goal …

This study is checking how safe ATGAM is for people with moderate to severe aplastic anemia, a condition where the bone marrow doesn't make enough blood cells. Only one person is taking part, and they will be watched for 24 weeks to see if any side effects happen. The goal is to …

This study looks at whether adding methadone to the usual pain medicine (morphine) can better control severe mouth pain in children aged 6 to 18 who are getting a stem cell transplant for conditions like leukemia or aplastic anemia. The mouth pain, called mucositis, is a common s…

This study follows people with aplastic anemia who previously received romiplostim in earlier clinical trials. The goal is to see how well their blood cell counts recover over up to 5 years and to monitor any long-term side effects. No new treatment is given; participants are sim…