New cord blood matching method could expand transplant access for blood cancer patients
NCT ID NCT01810588
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests a new approach to stem cell transplants for people with blood cancers like leukemia and lymphoma. Patients receive a combination of umbilical cord blood and stem cells from a family member, with the cord blood chosen based on specific genetic markers rather than just cell count. The goal is to see if this matching method leads to successful engraftment and better long-term survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- stem cell transplant (haploidentical donor cells and umbilical cord blood)
- What this could lead to
- If successful, this could make stem cell transplants safer and more available for people with blood cancers who lack a perfect donor match.
- What could go wrong
- This is a mid-stage trial with 270 participants, so results are not yet proven. The procedure carries risks like infection, graft failure, and side effects from chemotherapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Chicago Medical Center
Chicago, Illinois, 60637, United States
-
Weill Cornell Medical College
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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