New transplant method may save lives without causing more harm

NCT ID NCT01659606

First seen Jan 11, 2026 · Last updated May 11, 2026 · Updated 10 times

Summary

This study tests a bone marrow transplant method that avoids harsh drugs and radiation, which can worsen lung and liver disease or raise cancer risk in people with dyskeratosis congenita. About 40 participants with bone marrow failure will receive this gentler approach. The goal is to see if the transplant works safely and improves survival.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Boston Children's Hospital (pediatric patients)

    Boston, Massachusetts, 02115, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Mercy Hospital Kansas City

    Kansas City, Missouri, 64108, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Dana-Farber Cancer Institute (adult patients)

    Boston, Massachusetts, 02115, United States

  • Fred Hutch/University of Washington/Seattle Children's Cancer Consortium

    Seattle, Washington, 98109, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Karolinska University Hospital

    Stockholm, Sweden

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Oslo University Hospital

    Oslo, Norway

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.