APLASTIC ANEMIA

This study is testing a modified, gentler two-step method to prepare patients for a stem cell transplant. The goal is to reduce the risk of death from the transplant procedure itself for people with various blood cancers and disorders. Researchers are comparing two lower-intensit…

This study is monitoring the safety and effectiveness of the drug eltrombopag in children with aplastic anemia who are starting a specific treatment for the first time. It will follow about 10 children, aged 6 to 18, for one year to track any side effects and see how well their b…

This study is testing if a combination of home-based exercise training and a dietary supplement can help young people who have survived a bone marrow transplant. The goal is to rebuild lost muscle mass and improve their overall fitness and heart health. Researchers will compare t…

This early study is testing if a drug called Darzalex Faspro can safely lower harmful antibodies in patients with blood cancers. Lowering these antibodies may allow patients who are currently ineligible to receive a potentially life-saving stem cell transplant from a donor. The s…

This study is observing how well umbilical cord blood stem cells from unrelated donors work for patients with serious blood cancers and disorders. Researchers will track how quickly patients' blood counts recover, how often the transplant fails, and the rates of disease relapse a…

This study is testing a combination of four drugs to see if they can improve blood counts in adults with aplastic anemia or low-risk myelodysplastic syndrome (MDS). The treatment aims to calm an overactive immune system that may be attacking the bone marrow, while also boosting w…

This study is testing whether adding the drug ruxolitinib to standard medications can better prevent a dangerous complication called graft-versus-host disease (GVHD) after a bone marrow transplant. It focuses on adults over 40 with acquired aplastic anemia, a serious blood disord…

This study is testing if giving a drug called emapalumab right after diagnosis can help children and young adults with severe aplastic anemia. Aplastic anemia is a rare condition where the bone marrow stops making enough blood cells. Researchers want to see if adding emapalumab e…

This study aims to create and test a prediction tool to identify which pregnant women with aplastic anemia are at highest risk for serious complications. Aplastic anemia is a rare blood disorder that makes pregnancy very dangerous for both mother and baby. Researchers will follow…

This study is testing a new family communication tool called 'Let's Get REAL' to help children and teenagers be more involved in decisions about their stem cell or cellular therapy treatments. Researchers will work with 24 young patients (ages 8-17) and their parents to see if th…

This study is collecting information about how patients with blood cancers and disorders respond to stem cell transplants in the high-altitude Tibetan region. Researchers are enrolling 1000 patients and their donors to track treatment patterns, recovery times, survival rates, and…

This study aims to gather detailed information on many different blood diseases in China, including cancers like leukemia and lymphoma, and conditions like hemophilia. It will follow 2,300 patients to learn how common these diseases are, what treatments patients receive, how well…