New stem cell protocol offers hope for older adults with aplastic anemia
NCT ID NCT06646497
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a stem cell transplant method for adults aged 40 to 60 with severe aplastic anemia that has not improved or has returned after standard drug therapy. The approach uses a special drug after transplant to lower the risk of graft-versus-host disease, a common and serious complication. About 52 participants will receive this optimized transplant to see if it improves survival without severe side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHRU Nancy
RECRUITINGNancy, France
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CHU Amiens
RECRUITINGAmiens, France
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CHU Angers
RECRUITINGAngers, France
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CHU Besançon
RECRUITINGBesançon, France
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CHU Bordeaux
RECRUITINGBordeaux, France
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CHU Caen
NOT_YET_RECRUITINGCaen, France
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CHU Grenoble Alpes
RECRUITINGGrenoble, France
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CHU Lille
NOT_YET_RECRUITINGLille, France
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CHU Limoges
RECRUITINGLimoges, France
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CHU Lyon Sud
RECRUITINGLyon, France
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CHU Montpellier
RECRUITINGMontpellier, France
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CHU Nantes
RECRUITINGNantes, France
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CHU Nice
RECRUITINGNice, France
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CHU Poitiers
RECRUITINGPoitiers, France
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CHU Rennes
NOT_YET_RECRUITINGRennes, France
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CHU Saint Etienne
RECRUITINGSaint-Etienne, France
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CHU Strasbourg
RECRUITINGStrasbourg, France
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CHU Toulouse
RECRUITINGToulouse, France
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HNIA Percy
RECRUITINGClamart, France
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Henri Becquerel
NOT_YET_RECRUITINGRouen, France
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Hopital Necker - APHP
RECRUITINGParis, France
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Hôpital Henri Mondor AP-HP
NOT_YET_RECRUITINGCréteil, France
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Hôpital La Pitié Salpêtrière AP-HP
NOT_YET_RECRUITINGParis, France
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Hôpital d'Estaing
RECRUITINGClermont-Ferrand, France
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Institut Paoli Calmettes
NOT_YET_RECRUITINGMarseille, France
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Saint Louis hospital
RECRUITINGParis, France, 75010, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a drug revive blood cell production in children with aplastic anemia?
- Could a platelet-boosting drug shorten recovery after stem cell transplants?
- A common antioxidant may help platelets recover faster after stem cell transplant
- Could a cancer antibody reboot blood production in aplastic anemia?
- Triple therapy aims to overcome antibody barrier in Half-Matched stem cell transplants
- Promising combo for aplastic anemia trial pulled before start