AMYLOIDOSIS

This study tested whether adding daratumumab to standard chemotherapy (CyBorD) helps people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. Over 400 adults took part. The goal was to see if the combination leads to better blood resp…

This study tested whether a combined PET/MR scan using a radioactive tracer called F-18 florbetapir can detect amyloid deposits in the nerves of people with systemic amyloidosis. Eight adults with confirmed nerve amyloidosis or other nerve diseases were scanned to see if the trac…

This study tested a new imaging agent (124I AT-01) used with PET/CT scans to see how well it can measure amyloid deposits in organs like the heart, kidneys, liver, and spleen. 33 adults with systemic amyloidosis (AL or ATTR types) received the agent and were scanned twice to chec…

This study looked at 51 adults with cardiac amyloidosis, a condition where protein buildup damages the heart. Researchers tested their sense of smell and taste to see how common these problems are. The goal is to find early warning signs that could lead to faster diagnosis and tr…

This study followed 37 people who carry a genetic mutation for hereditary ATTR amyloidosis but do not yet have symptoms. Over five years, researchers measured a specific misfolded protein in the blood to see if it changes when the disease starts or when treatment is needed. The g…

This study looked at medical records of 721 Russian patients who had surgery for carpal tunnel syndrome to see how many also have a rare inherited nerve disease called hereditary transthyretin amyloidosis. The goal was to measure how common this disease is in that group. No treat…