AMYLOIDOSIS
Clinical trials for AMYLOIDOSIS explained in plain language.
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Breakthrough trial shows promise for controlling deadly Organ-Damaging disease
Disease control CompletedThis large, completed Phase 3 trial tested whether adding a drug called daratumumab to a standard three-drug therapy (CyBorD) works better for people newly diagnosed with AL amyloidosis. AL amyloidosis is a serious disease where abnormal proteins build up and damage organs like t…
Matched conditions: AMYLOIDOSIS
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC
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New scan aims to spot hidden nerve damage
Diagnosis CompletedThis study tested whether a special combined PET/MR scan could help doctors see amyloid protein buildup in the nerves of patients with amyloidosis. Researchers compared scan results from 8 patients with confirmed nerve amyloidosis to patients with other nerve diseases. The goal w…
Matched conditions: AMYLOIDOSIS
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Apr 01, 2026 14:41 UTC
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Scientists hunt for early warning signs of a silent killer
Knowledge-focused CompletedThis study aimed to understand how a serious inherited disease called hereditary transthyretin amyloidosis begins. Researchers followed 37 people who carry the disease gene but had no symptoms, tracking a specific protein in their blood over five years. The goal was to see if thi…
Matched conditions: AMYLOIDOSIS
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists test new scan to track deadly protein buildup
Knowledge-focused CompletedThis study tested a new radioactive imaging tracer called 124I AT-01. It was given to 33 people with systemic amyloidosis, a disease where harmful proteins build up in organs. The main goal was to see if PET/CT scans using this tracer could measure the protein buildup in the hear…
Matched conditions: AMYLOIDOSIS
Phase: PHASE2 • Sponsor: Attralus, Inc. • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Could a lost sense of smell be an early warning sign for a serious heart condition?
Knowledge-focused CompletedThis study aimed to understand how common smell and taste problems are in people with cardiac amyloidosis, a serious heart disease. Researchers tested 51 patients to see if these sensory issues could be an early warning sign that might help doctors diagnose the heart condition so…
Matched conditions: AMYLOIDOSIS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC