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Hidden nerve disease found in carpal tunnel patients?

NCT ID NCT06414746

Completed Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study in Russia checked how many people with carpal tunnel syndrome also have a rare inherited nerve condition called hereditary transthyretin amyloidosis. Researchers reviewed medical records of 721 patients and will test some for the genetic mutation. The goal is to understand how common this hidden disease is in this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify hidden cases of hereditary transthyretin amyloidosis earlier in patients with carpal tunnel syndrome.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve health. Results may not apply outside Russia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyloidosis carpal tunnel syndrome familial amyloid neuropathy polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYLOIDOSIS CARPAL TUNNEL SYNDROME HEREDITARY TRANSTHYRETIN AMYLOIDOSIS POLYNEUROPATHY

Contacts and locations

Locations

  • Research Site

    Arkhangelsk, Russia

  • Research Site

    Barnaul, Russia

  • Research Site

    Chelyabinsk, Russia

  • Research Site

    Irkutsk, Russia

  • Research Site

    Kazan', Russia

  • Research Site

    Krasnodar, Russia

  • Research Site

    Moscow, Russia

  • Research Site

    Nizhny Novgorod, Russia

  • Research Site

    Rostov-on-Don, Russia

  • Research Site

    Saint Petersburg, Russia

  • Research Site

    Samara, Russia

  • Research Site

    Ufa, Russia

  • Research Site

    Yekaterinburg, Russia

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