ADOLESCENT

This study aims to find the best way to involve parents or caregivers in helping teens (ages 12-17) with mild alcohol use problems. Researchers are comparing three approaches: a program for the teen only, the same program plus a single live session for a parent, or the teen progr…

This study is testing a new combination of cancer drugs for children, teens, and young adults (ages 2-35) newly diagnosed with classical Hodgkin lymphoma. The main goal is to improve the rate of early, complete response to treatment, which could allow more patients to avoid radia…

This trial is a flexible 'master protocol' designed to test multiple new cancer drugs for children and young adults more efficiently. It will enroll about 105 participants with various cancers. As new promising drugs emerge, they can be added to the trial for testing, allowing re…

This study is testing if adding a low dose of the medication esketamine to standard electroconvulsive therapy (ECT) is more effective for treating severe depression in teenagers. Researchers will compare two groups of 110 adolescents each: one receiving esketamine with ECT and on…

This study is testing if giving tuberculosis (TB) preventive medicine immediately after a household member is diagnosed can stop children and teenagers from catching the infection. Researchers will compare kids who get the medicine right away to those who follow standard care, wh…

This study is testing whether a structured breathing practice is a practical and acceptable way to help teenagers with anxiety and depression. It involves 40 teens, ages 12-17, from both rural and non-rural areas. The main goal is to see if the breathing program is easy to use an…

This study is testing a new smartphone app designed to help adolescent and young adult cancer survivors manage symptoms of depression. Researchers want to find out which parts of the app, or which combination of parts, are most helpful in reducing these symptoms. The study will i…

This study is testing whether gentle, non-invasive brain stimulation can help reduce depression symptoms in teenagers with bipolar disorder. One hundred participants aged 12-18 will receive either real or fake stimulation for 10 days while continuing their regular care. Researche…

This study is testing whether a culturally adapted skills training program called START NOW is better than usual care at reducing depression and anxiety in adolescent refugees. Researchers will enroll 80 young migrants in Switzerland and randomly assign them to either the new tra…

This study is testing whether a specialized exercise program called the Schroth Method can help teenagers with an excessive forward curve in their upper spine. Researchers will see if these exercises improve back muscle strength, reduce pain, and lead to better sleep and quality …

This study aims to understand the personal experiences of teenagers with anorexia nervosa, their parents, and their healthcare providers regarding psychiatric medications. Researchers will conduct interviews with 90 participants to learn about their perceptions, feelings, and the…

This study aims to collect normal walking and movement data from healthy children and teenagers. Researchers will measure how 40 participants, aged 3 to 25, walk and move using special cameras and floor sensors. This 'normal' data will be used as a comparison to help doctors bett…

This study aims to understand how trauma therapy helps teens with PTSD by looking at brain changes. Researchers will scan the brains of 180 teens before and after each phase of therapy to see which parts of the brain change during treatment. The goal is to learn how therapy works…

This study aims to better understand depression in teenagers by closely observing them. Researchers will track 1000 teens with moderate to severe depression using wearable devices, brain scans, and blood tests. The goal is to find patterns that could help predict how well treatme…